Select Country

 
877-783-6728 (877-StemSave)

StemSave Blog

Phase III Clinical Trial For Critical Limb Ischemia Utilizes Stem Cells

Posted by davids@stemsave.com on Feb 2, 2018 1:50:00 PM

0517_EVT_CFAlex_Fig4.pngPhase III clinical trials were announced for an autologous [the patient’s own] stem cell treatment to restore blood vessels and reestablish blood flow following critical limb ischemia (CLI). Ischemia is a lack of blood to an area in the body, typically due to a blood clot, and is common in diabetics and other patients whose conditions result in damage or clotting in the blood vessels. In extreme cases, ischemia can lead to painful ulcers, gangrene and even amputation, given that cells in the area of decreased blood flow begin to die rapidly. The treatment seeks to facilitate re-vascularization through the administration of both blood stem cells and endothelial progenitor cells, which form the walls of blood vessels.

Read More

Topics: stem cell treatments, regenerative medicine, critical limb ischemia

Stem Cell Graft Receives FDA Approval

Posted by pamela@stemsave.com on Jan 29, 2018 11:58:31 AM

images.jpg

The FDA has approved a novel synthetic scaffold that would allow stem cells to regrow bone more efficiently. The proprietary technology, Osteo-P [from Molecular Matrix Inc.], replaces the use of bone grafts and utilizes the patient’s own stem cells to regrow bone following trauma or injury. The Osteo-P, a scaffold made of carbohydrate [sugar] polymer, is an improved alternative to current bone grafting procedures in that it enables the body’s own stem cells to regenerate bone in aggregate, and it is resorbed by the body as it is replaced by the newly formed bone.

Read More

Topics: bone regeneration, FDA approval, stem cell graft

Stem Cells Alleviate Airway Hypersensitivity in Asthma

Posted by maxi@stemsave.com on Jan 24, 2018 1:51:09 PM

asthma-s16-man-inhaler.jpg

The immunomodulatory properties of mesenchymal stem cells [MSCs] are being tested to relieve the symptoms of asthma - airway inflammation which results in difficulty breathing. Asthmatic symptoms are caused by the body’s hypersensitive immune response to inhaling harmless allergens that trigger inflammation, which constricts airways and causes breathing to become extremely difficult, requiring an inhaler to counteract the inflammation. When administered in an animal model, mesenchymal stem cells (the same type of stem cells found in teeth) have successfully produced anti-inflammatory factors and neuropeptides that counteracted airway hypersensitivity and the production of pro-inflammatory receptors.

Read More

Dentistry Continues Its String of High Job Rankings

Posted by pamela@stemsave.com on Jan 22, 2018 1:24:47 PM

1.jpg

For the past 6 years, dentistry has consistently ranked in the top three of U.S. News and World Report’s annual job review.  This year dentistry took the #1 healthcare rank and the #2 overall rank (Overall Rank – 2013: #1  2014: #3  2015: #1  2016: #2  2017: #1  2018:  #2.) Dentists continue to enjoy an extremely low unemployment rate (0.4%), high job satisfaction and above average flexibility of hours. Though becoming a Dentist is a rigorous academic process; with undergraduate studies in the sciences and mathematics, followed by years of Dental School and residency, the profession remains particularly rewarding. Dentists are also playing a key role in the future of medicine by contributing to regenerative treatments through stem cell banking. Helping extract teeth for stem cell banking puts Dentists on the cusp of cutting edge breakthroughs and treatments, helping their patients acquire biological insurance in the form of stem cells and safeguarding their families against future trauma and illnesses.

Read More

Topics: dentistry, stem cell treatments

Treating Type I Diabetes with Stem Cells

Posted by maxi@stemsave.com on Jan 8, 2018 1:21:38 PM

Researchers at Cornell University are working on a stem cell-infused implant that could cure insulin deficiency for diabetics. Type I diabetes results from inadequate or malfunctioning insulin-producing beta cells in the islets of the pancreas, as well as an autoimmune response that attacks the body's insulin-producing cells. This treatment utilizes stem cells and directs them to differentiate into these cells. As opposed to daily insulin injections, the treatment is designed to provide a long-term solution that eliminates the need to constantly monitor blood sugar. It utilizes a naturally derived hydrogel to create a thread packed with stem cells induced to become pancreatic islets which is then implanted into the abdomen. Additionally, the treatment addresses what no other current treatment addresses: the body’s immune system attacking the insulin-producing cells. Encasing the cells protects them from the autoimmune response, increasing their efficacy and lifespan. 

Read More

Topics: Type-1 Diabetes, stem cell treatments, regenerative medicine, stem cell diabetes treatment, pancreatic islet cell regeneration, stem cell implant

Eradicating HIV with Stem Cells

Posted by anna@stemsave.com on Jan 3, 2018 2:00:00 PM

UCLA researchers are using stem cells and gene therapy to reverse the effects of HIV. The treatment utilizes stem cells to carry the chimeric antigen receptor (CAR) genes that have been successfully used to treat leukemia and are being explored for other cancers. The modified stem cells can trigger the immune system to specifically target and destroy HIV infected cells without harming nearby healthy cells. The stem cells carrying the gene are able to directly interrupt the mechanism between the virus and body cell surface receptors that allow the virus to infect the cells by binding to the virus and destroying it.

Read More

Topics: HIV, regenerative medicine, HIV treatment, CAR T Cell Therapy, stem cell HIV treatment

Type 2 Diabetes Mellitus - Stem Cell Clinical Trials

Posted by devin@stemsave.com on Dec 19, 2017 4:45:00 PM

In several clinical and animal studies, researchers are utilizing mesenchymal stem cells (MSCs) to treat Type II Diabetes Mellitus (T2DM). Type 2 Diabetes affects approximately 415 million people worldwide, with diabetes mellitus (DM) further exacerbating diabetes’ adverse health effects. Symptoms of DM are caused by both a lack of insulin, as-well-as an intolerance to the scarce amount of insulin that is produced by the pancreatic islet cells. DM is typically a precursor to ischemic heart disease, stroke, blindness and chronic kidney disease with no effective treatments currently available to prevent these complications. With previous treatments using donated organs and insulin producing cells proving unsuccessful, MSCs are emerging as an extremely effective tool to restore normal function to the pancreatic islet cells and alleviate the other symptoms of DM. MSCs (the same type of stem cells that are found in teeth) not only normalize natural insulin levels, but also help ameliorate insulin resistance in the body’s tissues by creating a favorable microenvironment.

Read More

Topics: pancreatic beta cells, type 2 diabetes, mesenchymal stem cells, diabetes mellitus, stem cell diabetes treatment, pancreatic islet cell regeneration

Treating Muscular Dystrophy with Stem Cells

Posted by taylor@stemsave.com on Dec 13, 2017 4:45:00 PM

UCLA researchers have developed a potential stem cell based treatment for Duchenne Muscular Dystrophy (DMD). This degenerative muscular disorder - caused by a genetic mutation in a protein essential for skeletal muscle function - primarily affects young men and boys, degenerating skeletal muscle to the point where it eventually wastes away. This severe degeneration of skeletal muscle results in almost a complete lack of voluntary movement. The UCLA team used the gene editing technology, CRISPR, to repair the mutated gene for the protein in stem cells obtained from the subjects and reintroduced the re-programmed muscle cells back into the subjects. In an animal model, the re-programmed cells successfully produced the dystrophin protein, reversing the degeneration of the skeletal muscle. The team has also conducted a second set of biological markers to ensure complete differentiation into adult muscle cells.  

Read More

Topics: Duchenne Muscular Dystrophy, regenerative medicine, stem cell treatment

Facilitating Rotator Cuff Tear Repairs with Stem Cells

Posted by davids@stemsave.com on Dec 7, 2017 4:45:00 PM

The Hospital for Special Surgery has been awarded an $800,000 grant to conduct a Phase II clinical trial utilizing autologous (the patient’s own) stem cells to help mend rotator cuff tears. This sizable grant will be used to treat one of the most common musculoskeletal conditions, particularly in athletes. Surgical repair for rotator cuff tears leave patients with resilient discomfort and pain, and many patients re-tear the muscle and are unable to return to full capacity. Stem cells can ameliorate the treatment process by facilitating recovery. The trial will investigate the efficacy of stem cells in skeletal muscle and tendon tissue regeneration, as well as the reduction of inflammation.

Read More

Topics: regenerative medicine, muscle regeneration, rotatore cuff repairs

Stem Cells Reverse MS in Breakthrough Clinical Trial

Posted by taylor@stemsave.com on Dec 1, 2017 12:30:00 PM

A team of researchers at the Hadassah Medical Center in Israel has developed a unique method of applying a patient’s own stem cells to restore mobility following progressive multiple sclerosis (MS). MS is an autoimmune disorder in which the body attacks its own neurons and affects millions of people worldwide. Severely progressive MS leads to complete loss of limb function, memory problems, seizures, and even systemic organ failure. This groundbreaking, double-blind, Phase II clinical trial successfully administered autologous (the patient’s own) mesenchymal stem cells, which were cultured and expanded to clinically significant numbers, and then applied directly into the spinal fluid. The treatment simultaneously addressed the two problems of MS - inflammatory immune response and the destruction of the outer coating of neurons that allows for quick signal transduction thereby engendering a significant increase in efficacy.

Read More

Topics: multiple sclerosis, MS, patient's own mesenchymal stem cells, mesenchymal stem cells, autologous stem cells, multiple sclerosis treatment

AAOMS

AAOMS - American Association of Oral and Maxillofacial Surgeons

 

As the industry leader, StemSave is the only stem cell banking service to be designated as an ASI approved program.

Subscribe to Email Updates

Join our Newsletter

Recent Posts

Posts by Topic

see all