Wan-Ju Li and Tsung-Lin Tsai, researchers at the University of Wisconsin-Madison, have developed a more efficient method to regrow large masses of bone. Using the proteins lipocalin-2 and prolactin, the researchers were able to slow and neutralize senescence, a naturally occurring process that negatively impacts the ability of stem cells to divide and grow, thereby preserving the regenerative capabilities of the mesenchymal stem cells and facilitating bone growth. The combination of these two proteins in culture provides sustenance for the stem cells to remain in prime condition until they are ready to be implanted into the patient.
"We found that [lipocalin-2 and prolactin] are critical in regulating the fate of mesenchymal stem cells," states Wan-Ju Li, a professor at UW- Madison. He also goes on to add, "We're seeking better treatments for bone repair," given that the discovery of having these proteins in culture with stem cells can improve the current method for bone regrowth.
Advances in stem cell based regenerative treatments are creating more effective treatment options for patients suffering from a wide variety of disease, trauma and injury. To learn more about stem cells and how families can bank their own valuable stem cells visit StemSave or call 877-783-6728 (877-StemSave) today.
The Future of Regenerative Medicine is Now™
To view the full article, click here.