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Drug Testing Against Cancer Using Stem Cells

Posted by artgreco@stemsave.com on Aug 8, 2016 4:51:43 PM

Researchers at Johns Hopkins Kimmel Cancer Center have developed a system that uses differentiated human stem cells to expedite the testing of existing drugs that might work against rare cancers. By transforming human stem cells into an aggressive form of pediatric brain cancer, medulloblastoma, they can be compared to cancer cells already tested against existing drugs.

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Topics: Cancer, stem cell differentiation, stem cell treatments, drug screening, clinical research

Stem Cells Zero in on Tumors

Posted by davids@stemsave.com on May 25, 2016 2:31:00 PM

A collaborative investigation by researchers at Brigham and Women's Hospital and Johns Hopkins University created a cancer treatment that utilizes mesenchymal stem cells and microparticles. Both components of the treatment are engineered to specifically target and kill cancer cells.

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Topics: bioengineering, tumors, chemotherapy, Cancer, StemSave blog, mesenchymal stem cells, microparticles

Stem Cells Revitalize Chemotherapy Treated Cells

Posted by davids@stemsave.com on Nov 13, 2015 2:12:00 PM

Innumerable studies [using animals] have been conducted pertaining to the regenerative capabilities of stem cells to restore cell function in cells/tissue exposed to chemotherapy. In one such study, scientists from Egypt's Mansoura Medical School injected bone marrow stem cells in chemotherapy treated animals and documented the regeneration of ovarian tissue and an increase in follicular count.

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Topics: stemsaveblog, clinical trials, chemotherapy, Cancer, mesenchymal stem cells, ovarian tissue

Stem Cells Ameliorate Post Prostatectomy Side Effects

Posted by pamela@stemsave.com on Oct 30, 2015 2:47:00 PM

Mesenchymal stem cell therapy has demonstrated yet another application in repairing tissue damage. Mesenchymal stem cells (MSCs) greatly improved urinary continence and erectile function after radical prostatectomy (RP) in animal studies. These conditions are common side effects of surgical treatment for human prostate cancer.

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Topics: stemsaveblog, prostate, Cancer, erectile dysfunction, mesenchymal stem cells

Silk Scaffold Supplies Salivary Gland Stem Cell Solution

Posted by taylor@stemsave.com on Aug 19, 2015 11:31:58 AM

 

Purified silk strands provided the scaffolding for a matrix of rat salivary cell glands developed from stem cells, according to new research from The University of Texas Health Science Center at San Antonio. Salivary stem cells have historically been difficult to grow in culture while retaining their function. Silk was selected as the cell scaffolding because it is organic (biodegradable), flexible, porous – providing amply access to oxygen – and does not cause inflammation.

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Topics: scaffold, stemsaveblog, regerative medicine, Cancer, mesenchymal stem cells, autologous stem cells, tissue regeneration, salivary gland, saliva, sjogren's syndrome

Stem Cells Regulated by Cellular Environment.

Posted by barb@stemsave.com on May 26, 2015 12:45:51 PM

Recently published research from the Yale University Cancer Center has evaluated the effect of a stem cell’s surrounding area on whether or not the cell will grow or die.  The scientists, led by Kailin R. Mesa, observed stem cells on a hair follicle using live microscopic imaging to determine that the environment in which the stem cell is located plays a critical role in the fate of that cell.  Mesa’s team also observed that stem cells contain a feeding mechanism to rid the skin area of dead cells.

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Topics: saving stem cells, Cancer, Yale University, research, StemSave, mesenchymal stem cells, regenerative medicine, stem cells, adult stem cells

Healthy Lifestyle, Healthy Stem Cells – The Link between Stress and Stem Cell Efficiency.

Posted by artgreco@stemsave.com on Apr 10, 2015 11:07:00 AM

In a recently published article, scientists from the German Cancer Research Center [DKFZ] have detailed the risks of stress-induced stem cell activation to cause DNA damage. Stressful events within the body drive adult stem cells into high energy states of rapid cell division and DNA synthesis to produce blood or repair damaged tissue. But since the transition from dormancy to executing these complicated functions is so abrupt, DNA is more likely to be damaged, resulting in cell death or harmful mutations. 

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Topics: aging, Cancer, cancer research, DNA, healthy,, stress, DNA Damage,

Male Infertility Research Identifies Sperm-Producing Stem Cells.

Posted by taylor@stemsave.com on Nov 22, 2014 10:33:48 AM

A new method of identifying sperm-producing stem cells could lead to stem cell treatments for male sterility.

In a recent study conducted by the University Of Texas Southwestern Medical Center, scientists have discovered a rare line of stem cells involved in regulating spermatogenesis [the production of sperm cells]. Furthermore, these stem cells are resistant to chemotherapy and radiotherapy, which are toxic to the male germline and common causes for male infertility.

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Topics: Pre-mature, stemsaveblog, Debilitating Diseases, Stemcells, Cancer, autologousstemcells, young stem cells, Genitals

Esophagus Engineered with Stem Cells In-Vivo.

Posted by pamela@stemsave.com on Nov 20, 2014 9:52:41 AM

Scientists have utilized stem cells to engineer an esophagus without exogenous growth factors.

Researchers from the Saban Research Institute of Children’s Hospital Los Angeles have grown esophageal tissue in vivo (in the body) from stem cells without the use of exogenous growth factors. In an animal model, the scientists transplanted stem cells, as well as a simple biodegradable scaffold, and relied on the stem cells’ ability to migrate towards the tissue in need of repair. The cells then differentiated into the epithelial, muscle, and nerve cells to develop a healthy esophagus.

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Topics: stemsaveblog, Debilitating Diseases, Stemcells, Cancer, autologousstemcells

Stem Cells Immune to Damage from Leukemia Chemotherapy

Posted by artgreco@stemsave.com on Aug 6, 2014 6:09:26 AM

Certain stem cells have been found to be immune to the bone-degenerative side effects of chemotherapy used against leukemia.

A research team, led by Dr. Eric Darling of Brown University, has found a potential source of stem cells to protect children with acute lymphoblastic leukemia against the adverse effects of the chemotherapy drug methotrexate (MTX). Adipose-derived stem cells, which appear to be impervious to the bone-degenerative side effects of MTX, may allow children to undergo the chemotherapy treatment and then regain the lost bone tissue afterwards.

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Topics: Blood Cancer, stemsaveblog, Bone, Debilitating Diseases, Stemcells, Cancer, autologousstemcells, Blood vessel, young stem cells

AAOMS

AAOMS - American Association of Oral and Maxillofacial Surgeons

 

As the industry leader, StemSave is the only stem cell banking service to be designated as an ASI approved program.

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