Medical researchers from Keele University and Nottingham University have integrated remote controlled magnetic nanoparticles to incite the differentiation of stem cells into new bone tissue for the treatment of bone diseases, disorders, and injuries. In pre-clinical trials, the nanoparticles were coated with proteins that stimulate the stem cells, and then delivered directly to the damaged tissue via an external magnetic field.
In recent clinical trials, researchers at the National University of Ireland Galway have successfully utilized adult stem cells to treat patients with osteoarthritis. The treatment involves recovering the patients’ own [autologous] stem cells and then injecting the stem cells into cartilage to stimulate the regeneration of lost tissue.
Topics: osteoporosis, Fingers, Phase III, Bone loss, Joints, knee replacement, clinical trials, Bone, Debilitating Diseases, Arthritis, Stemcells, Feet, Rheumatoid Arthritis, Hip replacement, Knee, hip, autologousstemcells, cartilage, Cartilage degradation, stemsaveblog
Cartilage injuries can range from small lesions, such as those of athletes, to chronic injuries, such as cartilage degradation. Cartilage injuries, which are difficult to repair and have limited options for surgery, and usually results in a drastic affect on quality of life of afflicted individuals. In addition, the health, number and vitality of cartilage cells diminish with age.