Scientists at the Cincinnati Children’s Hospital Medical Centre have induced adult stem cells to differentiate into small clusters of gastric tissue that replicate the functions of the human stomach. The lab-made structures, known as “mini-stomachs”, were created by replicating the chemical pathways of early stage stomach development of stem cells in a petri dish.
As reported in a recent article in the New York Times, researchers from the National Cancer Institute have developed an immune system treatment for a woman afflicted with cholangiocarcinoma (bile-duct cancer) utilizing her own stem cells. The scientists, led by Dr. Steven A Rosenberg, identified T-cells in the woman’s immune system that specifically attacked the cancerous cells in her body. They then used her stem cells to grow billions of these T-cells in a laboratory, and then infused the T-cells back into her bloodstream. After 18 months of the treatment, known as adoptive cell therapy, the woman experienced considerable reduction of tumor size and quantity.