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Treating Chronic Lung Disease with Stem Cells

Posted by maxi@stemsave.com on Aug 16, 2017 4:45:00 PM

Researchers at the UNC School of Medicine and North Carolina State University have created a method of obtaining and culturing stem cells to treat chronic and potentially fatal lung inflammation. Chronic inflammation in the lungs causes the formation of scar tissue that inhibits proper oxygenation of vital organs, like the heart and brain. Idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD) are some of the most common results of chronic inflammation. With many IPF patients not surviving past 5 years following diagnosis, this treatment could significantly prolong their lives. The treatment is done by isolating a patient’s own lung stem cells through biopsy, then culturing and expanding them to clinically relevant numbers. In an animal model, the subjects were induced to have scarring and inflammation in the lungs to mimic IPF in humans. Those that were injected with their own stem cells showed significant improvement in lung function compared to those that received a placebo.

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Topics: COPD, IPF, regenerative medicine, stem cell treatments, chronic lung disease treatment

AAOMS

AAOMS - American Association of Oral and Maxillofacial Surgeons

 

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