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An Eye for a Tooth: Corneal Blindness Treatment Advances With The Use Of Dental Stem Cells.

Posted by barb@stemsave.com on Mar 2, 2015 8:11:11 AM

Dental Stem Cells may hold the potential to cure corneal blindness.

Ophthalmologists James L Funderburgh, Ph.D. and Fatima Syed-Picard, Ph.D. from the University of Pittsburgh have devised a method for treating corneal blindness by utilizing dental pulp stem cells. The researchers harvested the stem cells from molars discarded during routine extraction and induced the cells to differentiate into keratocytes [corneal cells]. They then seeded the cells onto a nanofiber scaffold, allowing them to grow into fully developed, functional corneas capable of restoring eyesight.

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Topics: Eye, stemsaveblog, Debilitating Diseases, Stemcells, Teeth, autologousstemcells, dentalstemcells, dental pulp stem cells, Blindness

Stem Cell Awareness Day 2014

Posted by Kelsey StemSave on Oct 8, 2014 11:25:03 AM

The California Institute of Regenerative Medicine has coordinated Stem Cell Awareness day to highlight all of the progress that stem cells already made for patients around the world.

Today, stem cells are rightfully perceived as the future of regenerative medicine, set to bring the marvels of science fiction into reality. But in looking ahead at all of the promise that stem cells hold for the future, it becomes easy to miss the scientific advances made to date for the millions of people around the world suffering from disease, trauma, and injury. Thus, today marks Stem Cell Awareness Day: a global celebration of stem cell research coordinated to highlight the treatments and therapies currently in development to create personalized regenerative therapies for patients.

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Topics: neural stem cells, stemsaveblog, clinical trials, Stemcells, translational genomics, autologousstemcells, dentalstemcells, dental pulp stem cells, nanotechnology, young stem cells

Harnessing the Power of Stem Cells

Posted by hunter@stemsave.com on Jul 20, 2014 12:12:07 PM

Scientists have developed a method for increasing the survival rate, and therefore the effectiveness, of transplanted mesenchymal stem cells.

A team of scientists from the Harvard Stem Cell Institute and the Boston Children’s Hospital have developed a method to increase the survival rate, and therefore the effectiveness, of transplanted mesenchymal stem cells [MSCs]. In an animal model, Dr. Juan Melero-Martin and his team of researchers co-transplanted MSCs with blood vessel-forming cells, enabling the stem cells to survive longer in a patient to reach their full regenerative potential.

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Topics: Muscular Dystrophy, Skin, neural stem cells, stemsaveblog, Heart Failure, Debilitating Diseases, Stemcells, autologousstemcells, dentalstemcells, dental pulp stem cells, young stem cells

Dental Stem Cells Differentiated into Brain-like Cells for Stroke Patients

Posted by barb@stemsave.com on May 13, 2014 6:17:06 AM

Scientists have discovered the ability of dental pulp stem cells to grow into brain-like neurons.

Researchers from the University of Adelaide, led by Dr. Kylie Ellis, have discovered that dental pulp stem cells [DPSC] have the ability to differentiate into complex networks of cells closely resembling neurons found in the brain. According to Dr. Ellis, “Stem cells from teeth have great potential to grow into new brain or nerve cells, and this could potentially assist with treatments of brain disorders, such as stroke.” She goes on to say “ultimately, we want to be able to use a patient’s own stem cells for tailor-made brain therapy that doesn’t have the host rejection issues commonly associated with cell-based therapies. Another advantage is that dental pulp stem cell therapy may provide a treatment option available months or even years after the stroke has occurred.” Current drug treatment therapies for stroke victims must be administered almost immediately following the stroke – within hours. This severely limits their application as most stroke victims don’t have access to these treatments within that timeframe.

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Topics: stemsaveblog, Brain, clinical trials, Debilitating Diseases, Stemcells, autologousstemcells, dentalstemcells, Neurodegenerative disease

Mayo Clinic Advances Stem Cell Treatment for Heart Disease

Posted by maxi@stemsave.com on Nov 15, 2013 12:47:32 PM

Mayo Clinic Researchers have used autologous stem cells to treat heart disease

Mayo Clinic researchers from the Center of Regenerative Medicine have utilized a patient’s own stem cells in a novel treatment for heart disease. The treatment involves harvesting the patient’s own stem cells, expanding and differentiating them in-vitro [outside the body] and transplanting them back into the patient. As a result of the successful initial study, a wider clinical trial is planned.

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Topics: Heart, stemsaveblog, Heart Failure, clinical trials, Debilitating Diseases, Stemcells, Heart Attack, dentalstemcells, heart disease

Stem Cells Promote Regrowth of Neural Cells Following Traumatic Brain Injury

Posted by taylor@stemsave.com on Nov 1, 2013 8:29:36 AM

Transplanted neurogenic stem cells recruit host neural stem cells to site of TBI for repair.

Researchers at the University of South Florida have successfully used adult stem cells to repair traumatic brain damage in neurologically impaired mice. Prior to the study, hypotheses on how stem cells may provide treatment for neurological disorders were limited. However, the results of this experiment provide a new theory: stem cells replace dying cells while attracting other stem cells from uninjured regions of the brain to the damaged portions for continued neural cell replenishment. In the words of Principal Investigator Dr. Cesar Borlongan, "The transplanted stem cells serve as migratory cues for the brain's own neurogenic cells."

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Topics: traumatic brain injuries, neural stem cells, stemsaveblog, Brain, Stemcells, autologousstemcells, dentalstemcells

Stem Cell Diabetes Treatment Option Advances

Posted by devin@stemsave.com on Aug 3, 2013 9:26:33 AM

In an early stage study recently carried out by the Institute of Kidney Diseases and Research Center (IKDRC), a treatment developed by the IKDRC utilizing Insulin Secreting Cells (ISC), derived from the patient’s own mesenchymal stem cells, shows that the need for insulin doses decreased by an average of 50% when the ISCs were implanted in patients.

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Topics: stemsaveblog, Diabetes, Type-1 Diabetes, Stemcells, autologousstemcells, dentalstemcells, dental pulp stem cells

Dental Pulp Stem Cells to Regenerate Teeth

Posted by barb@stemsave.com on Jul 19, 2013 11:55:40 AM

Utilizing dental pulp stem cells, researchers at Japan’s National Center for Geriatrics and Gerontology have developed a stem cell treatment for tooth decay by restoring a tooth’s structure and function. In the study, involving canine subjects, researchers utilized the dog’s own dental pulp stem cells to repair damaged and compromised teeth. Given the success of the study, researchers have initiated clinical [human] trials.

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Topics: tooth decay, stemsaveblog, clinical trials, Stemcells, Teeth, autologousstemcells, dentalstemcells, dental pulp stem cells

WSJ Reports On Dental Stem Cells

Posted by hunter@stemsave.com on Jul 3, 2013 6:49:56 AM

 

Dental Pulp Stem Cells

The Wall Street Journal recently reported on current research involving dental pulp stem cells [DPSC]. Researchers worldwide, including StemSave’s Chief Scientific Adviser, Dr. Jeremy Mao of Columbia University, are making advances in restoring tooth tissue and regenerating entire teeth using dental pulp stem cells. Current studies are in the animal model stage but researchers anticipate entering human clinical trials in the near future.

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Topics: stemsaveblog, scientific advisors, Stemcells, Teeth, dentalstemcells, dental pulp stem cells

Researchers Utilize Mesenchymal Stem Cells [MCS] to Generate Cartilage Formation

Posted by devin@stemsave.com on Jun 17, 2013 9:11:40 AM

Knee Cartilage

Cartilage injuries can range from small lesions, such as those of athletes, to chronic injuries, such as cartilage degradation. Cartilage injuries, which are difficult to repair and have limited options for surgery, and usually results in a drastic affect on quality of life of afflicted individuals. In addition, the health, number and vitality of cartilage cells diminish with age.

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Topics: stemsaveblog, Joints, aging, Stemcells, dentalstemcells, cartilage, Cartilage degradation

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AAOMS - American Association of Oral and Maxillofacial Surgeons

 

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