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Stem Cells Treat Diabetic Kidney Disease

Posted by taylor@stemsave.com on Nov 2, 2015 3:03:00 PM

NHS Blood and Transplant is organizing a stem cell treatment protocol in Liverpool, England for patients with diabetes related kidney disease. The randomized controlled trial will compare injections of mesenchymal stem cells with placebo injections and study whether stem cells will slow down or halt tissue damage, removing the current reliance on dialysis or transplants.

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Topics: kidney disease, stemsaveblog, Diabetes, clinical trial, mesenchymal stem cells, regenerative medicine

Mesenchymal Stem Cells Promote Wound Healing

Posted by taylor@stemsave.com on Sep 25, 2015 2:18:00 PM

Researchers at the Interdisciplinary Stem Cell Institute at the University of Miami Miller School of Medicine have investigated the impact of mesenchymal stem cell exosomes in the treatment of chronic non-healing wounds. These conditions affect 6.5 million people with diabetes and paraplegia in the Unites States alone, at an estimated treatment cost of $25 billion per year.

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Topics: stemsaveblog, Diabetes, paraplegia, regenerative therapies, growth factors, mesenchymal stem cells, chronic pain, exosome

Type 1 Diabetes Reversed by Integrating Mesenchymal Stem Cells.

Posted by devin@stemsave.com on Feb 12, 2015 5:30:48 AM

MSCs and HCELL molecules track down islet cells and reverse inflammation.

According to a recently published study from the Brigham and Woman’s Hospital, mesenchymal stem cells [MSCs] have the ability to reverse type I diabetes by suppressing the auto-immune attack of islet cells. Although the MSCs cannot be directly injected into the pancreas, the researchers utilized the surface adhesion molecule HCELL to hone the stem cells in on the inflamed islets, allowing them to normalize blood sugar levels without the use of insulin.

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Topics: stemsaveblog, Diabetes, Type-1 Diabetes, Debilitating Diseases, Stemcells, autologousstemcells

Listen to Your Gut - “Mini-Stomachs” Built In-Vitro from Stem Cells.

Posted by anna@stemsave.com on Dec 19, 2014 10:29:32 AM

Scientists have engineered cellular clusters that mimic the functions of the stomach.

Scientists at the Cincinnati Children’s Hospital Medical Centre have induced adult stem cells to differentiate into small clusters of gastric tissue that replicate the functions of the human stomach. The lab-made structures, known as “mini-stomachs”, were created by replicating the chemical pathways of early stage stomach development of stem cells in a petri dish.

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Topics: stemsaveblog, Diabetes, stomach, Debilitating Diseases, Stemcells, Crohn's Disease, autologousstemcells, grants, cholangiocarcinoma, intestinal tissue

Insulin Producing Cells En-Masse

Posted by hunter@stemsave.com on Oct 28, 2014 10:45:33 AM

Scientists have accelerated stem cell differentiation to produce more insulin-producing beta cells.

Harvard University researchers have developed a technique to accelerate stem cell differentiation to produce massive amounts of the insulin-producing beta cells that are destroyed in patients with type-1 or type-2 diabetes. With an ample and readily available supply of beta cells, researchers are developing therapies that may someday allow patients to produce the precise amount of insulin required to control their blood sugar levels naturally – without the use of a pump or insulin shots.

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Topics: stemsaveblog, Diabetes, Debilitating Diseases, Stemcells, autologousstemcells

New York Times: The Eruption of Stem Cell Therapies.

Posted by taylor@stemsave.com on Sep 16, 2014 11:04:35 AM

Mr. Edgar Irastorza is one of thousands of people already benefiting from the progression of stem cell based therapies.

As reported on the front page of the New York Times Science section, clinical applications of stem cell based therapies are accelerating at a rate that will revolutionize the medical field in a matter of years. In the United States alone, there are currently over 4000 therapies in clinical trials for the treatment of heart disease, blindness, spinal cord injuries, diabetes, H.I.V., and other diseases, injuries, and traumas.

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Topics: Muscular Dystrophy, ALS, Parkinson's, Phase III, multiple sclerosis, Heart, stemsaveblog, Joints, Alzheimer's, burn injuries, Diabetes, Acute Myocardial Infarction, Brain, Heart Failure, clinical trials, Bone, Debilitating Diseases, Phase II, Arthritis, Stemcells, Teeth, autologousstemcells, cartilage, Amyotrophic lateral sclerosis, Brain Tumors, Blindness

Type 1 Diabetes Treatment Advance Utilizes Mesenchymal Stem Cells

Posted by devin@stemsave.com on Sep 13, 2014 6:18:57 AM

The transplantation of adult stem cells into a Type-1 Diabetes animal model has revealed the importance of blood vessels in pancreatic beta cell regeneration.

Researchers led by Dr. Habib Zaghouani from the University of Missouri have developed a potential cure to Type 1 Diabetes by utilizing mesenchymal stem cells [MSCs]. Although researchers anticipated that the MSCs would differentiate into new insulin producing pancreatic beta cells, they discovered that the stem cells fulfilled the more critical function of repairing damaged blood vessels, which in turn facilitated the regeneration of insulin producing pancreatic beta cells and the distribution of insulin across the body.

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Topics: stemsaveblog, Diabetes, Type-1 Diabetes, Debilitating Diseases, Stemcells, Bile duct, Blood vessel

Type 1 Diabetes Treatment Utilizes Stem Cells to Regenerate Pancreatic Beta Cells

Posted by hunter@stemsave.com on Mar 27, 2014 8:35:07 AM

Stem cells have been differentiated into pancreatic beta cells, providing a potential treatment for Type 1 Diabetes.

Researchers from the Gladstone Institutes have developed a potential treatment for Type 1 diabetes by differentiating stem cells into insulin-producing pancreatic beta cells. These new cells, when transplanted into animal models, lowered abnormally high glucose levels down to a more healthy level in just one week.

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Topics: stemsaveblog, Diabetes, Type-1 Diabetes, clinical trials, Debilitating Diseases, Stemcells, autologousstemcells

Stem Cell Diabetes Treatment Option Advances

Posted by devin@stemsave.com on Aug 3, 2013 9:26:33 AM

In an early stage study recently carried out by the Institute of Kidney Diseases and Research Center (IKDRC), a treatment developed by the IKDRC utilizing Insulin Secreting Cells (ISC), derived from the patient’s own mesenchymal stem cells, shows that the need for insulin doses decreased by an average of 50% when the ISCs were implanted in patients.

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Topics: stemsaveblog, Diabetes, Type-1 Diabetes, Stemcells, autologousstemcells, dentalstemcells, dental pulp stem cells

Stem Cell Treatment for Type-1 Diabetes Advances

Posted by barb@stemsave.com on Jun 14, 2013 9:16:22 AM

Millions of individuals around the world suffer from type-1 diabetes, three million in the US alone. Researchers at the University of Missouri, led by Dr. Habib Zaghouani, have developed a two pronged approach to curing the disease: they modulate the immune system with a drug that stops it from attacking the pancreas and use stem cells to regenerate and rebuild the insulin producing pancreatic beta cells.

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Topics: stemsaveblog, Diabetes, Type-1 Diabetes, Stemcells

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AAOMS - American Association of Oral and Maxillofacial Surgeons

 

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