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Hip Fracture Rehabilitation with Stem Cells

Posted by davids@stemsave.com on Aug 28, 2017 4:45:00 PM

Collaborating researchers from the University of California Davis Medical Center and the Second Xiangya Hospital of the Central-South University (Hunan, China)  are developing an autologous [the patient’s own] stem cell protocol to aid the rehabilitation process following a hip fracture.  With over 300,000 hip fractures in the US alone, and with many patients failing to return to an independent lifestyle following the fracture, the need for more effective rehabilitation methodologies is great; the mortality rate following a fracture is high as well. The team of researchers is focusing on the application of mesenchymal stem cells (MSCs) to facilitate the healing process and get patients back on their feet. When tested in an animal model, autologous MSCs were engineered to express a growth factor called bFGF, which directs the differentiation of these stem cells into osteoblasts that will later become bone. When injected back into the subject with a hip fracture, this growth factor also successfully promoted vascularization around the fracture site and the ossification of the bone.

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Topics: mesenchymal stem cells, regenerative medicine, autologous stem cells, hip fractures

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AAOMS - American Association of Oral and Maxillofacial Surgeons

 

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