Researchers from the Cincinnati Children’s Hospital Medical Centre have successfully grown functional human intestinal tissues by utilizing stem cells. After stimulating the stem cells with a “molecular cocktail” of chemicals and growth factors, the team observed as the cells developed into the mucosal lining and muscle layers, while exhibiting digestive functions such as nutrient uptake and responding to molecular signals.
Topics: Gastrointestinal cancer, stemsaveblog, ulcerative colitis, Debilitating Diseases, Stemcells, Crohn's Disease, Thanksgiving, autologousstemcells, intestinal tissue, small intestine, Inflammatory Bowel Disease
Researchers at MIT and Brigham and Women’s Hospital have developed a method of growing unlimited quantities of intestinal stem cells thus enabling them to better understand intestinal diseases and advance the development of more personalized and effective treatment options.
Inflammatory Bowel Disease (IBD) is a group of inflammatory conditions of the colon and small intestine. The major types of IDB are Crohn’s Disease and ulcerative colitis. In the US, approximately 1 million people suffer from diseases that fall under the category of IBD. Treatments for this disease ordinarily include steroids and immune-suppressors. However, researchers at Wake Forest have recently discovered a population of stem cells that may be able to treat IBD without the use of either steroids or immune-suppressors.