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Lung Regeneration Made Possible through Stem Cells.

Posted by anna@stemsave.com on Jan 26, 2015 8:34:32 AM

Scientists have found a stem cell line that specializes in restoring lung tissue

Jackson Laboratory scientists have identified the adult lung stem cells p63+/Krt5+ as the specific cell line that specializes in lung regeneration. In an animal model, professors Frank McKeon, Ph.D. and Wa Xian, Ph.D. observed as the p63+/Krt5+, which typically mature into the lungs’ alveoli, responded to lung damage caused by the H1N1 influenza virus by migrating to the sites of inflammation and restoring the lost tissue.

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Topics: Lungs, stemsaveblog, Debilitating Diseases, Stemcells, autologousstemcells

ARDS Treatment Integrates Proteins from Stem Cells.

Posted by hunter@stemsave.com on Sep 21, 2014 11:52:51 AM

Scientists have utilized Mesenchymal Stem Cells to reduce inflammation in the lungs of ARDS patients.

A recent study presented at the European Respiratory Society’s International Congress has developed a possible treatment for Acute Respiratory Distress Syndrome (ARDS) by using Mesenchymal Stem Cells [MSC] to reduce inflammation in the lungs. In an animal model, stem cells released proteins that stimulate macrophages (a type of white blood cell) to suppress the excessive immune response that can severely damage a patient’s lungs.

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Topics: Lungs, stemsaveblog, clinical trials, Debilitating Diseases, Stemcells, autologousstemcells

Human Lungs Successfully Grown in Lab via Stem Cells

Posted by devin@stemsave.com on Apr 27, 2014 7:48:58 PM

Scientists may have found a solution for immune rejection of lung transplants.

Researchers from the University of Texas Medical Branch have successfully grown human lungs in vitro [in a lab] by utilizing stem cells. The team of scientists, led by Dr. Michael Riddle, used a donated lung to engineer a scaffold outlining the lung’s architecture. Then, they seeded the scaffold with stem cells from the donor’s complementary lung to create a complete, functional, and healthy lung.

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Topics: Lungs, stemsaveblog, clinical trials, Debilitating Diseases, Stemcells, autologousstemcells

Bronchopulmonary Dysplasia Treatment for Preterm Infants Utilizes Mesenchymal Stem Cells [MSC].

Posted by hunter@stemsave.com on Mar 10, 2014 8:51:42 AM

Mesenchymal Stem Cell transplants may prevent preterm babies from developing BPD.

Researchers at the Samsung Medical Center and Biomedical Research Institute in Seoul, South Korea, have succeeded in treating and preventing Bronchopulmonary Dysplasia [BPD], a chronic lung disease affecting preterm infants. In a Phase 1 clinical trial, the research team was successful in transplanting mesenchymal stem cells to repair damage and underdevelopment within the infant’s lungs.

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Topics: Lungs, stemsaveblog, clinical trials, Debilitating Diseases, Phase II, Stemcells, autologousstemcells

Diamonds Are a Girl’s – and Stem Cell’s – Best Friend

Posted by devin@stemsave.com on Aug 27, 2013 7:30:38 AM

Nanodiamond

Scientists at Academia Sinica in Taiwan have used fluorescent nanodiamonds to track a single stem cell implanted into the lungs of mice. The tracking capability gives researchers insight into site specific interactions of stem cells and their surrounding environment.

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Topics: Lungs, stemsaveblog, Stemcells, nanotechnology

Research Shows Stem Cells May Reverse Lung Damage in Preemies

Posted by anna@stemsave.com on Dec 21, 2012 10:39:43 AM

 

 

 

 

 

 

 

 

 

Nearly half a million babies in the U.S. are born premature every year (that's roughly 1 in every 8 children). Many of them require medical assistance during the first weeks of life, especially due to their under-developed lungs. Babies that are born premature are often put on breathing machines as their lungs finish maturing, but there can be negative side effects of these measures: many children (as many as 10,000) develop a condition called bronchopulmonary dysplasia, or BPD.

But research headed by Bernard Thébaud, a neonatologist and senior scientist at the Ottawa Hospital Research Institute and CHEO Research Institute, demonstrates that mesenchymal stem cells (MSCs) can help repair damaged lungs in animal studies involving newborn rats, which have lungs that are roughly similar to a human fetus at 24 weeks of development.

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Topics: Pre-mature, Lungs, stemsaveblog, Stemcells, autologousstemcells

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AAOMS - American Association of Oral and Maxillofacial Surgeons

 

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