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ALS Study Utilizes Stem Cells to Illuminate the Role of Astrocytes in Neurodegenerative Disease.

Posted by pamela@stemsave.com on Apr 18, 2015 11:41:00 AM

Researchers led by Dr. Su-Chun Zhang at the University of Wisconsin-Madison Waisman Center are utilizing stem cells in a pre-clinical trial to determine the role of human astrocytes in neurodegenerative diseases such as ALS, Huntington’s disease, and Rhett Syndrome.  The team found that, upon integration into the central nervous system, stem cell-derived astrocytes from patients with ALS replace the astrocytes of the host while disrupting motor function, as though the host also had ALS.

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Topics: ALS, neural stem cells, stemsaveblog, autologous dental pulp stem cells, Amyotrophic lateral sclerosis, Neurodegenerative disease, neurological disease,, astrocytes

Multiple Sclerosis Treatment “Resets” Immune System through Stem Cell Transplantation.

Posted by maxi@stemsave.com on Apr 4, 2015 11:36:00 AM

In a recently published study, a team of researchers led by Dr. Giovanni Mancardi from the University of Genoa conducted a phase II clinical trial to compare the effectiveness of conventional multiple sclerosis [MS] therapy to intravenous stem cell transplantation.  Throughout the four year trial, the team found that, in addition to significantly decreasing disease progression and brain damage compared to MS drug mitoxantrone [MTX], the transplanted stem cells had migrated into the patients’ bone marrow and stimulated the generation of new, non-harmful immune cells, essentially resetting the immune system.

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Topics: multiple sclerosis, stemsaveblog, Brain, clinical trials, clinical trial, bone marrow, immune system, neurological disease,, university of genoa,, autoimmune attack, nerve stem cells,

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AAOMS - American Association of Oral and Maxillofacial Surgeons

 

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