A case study utilizing a patient’s own stem cells to treat rheumatoid arthritis demonstrated a drastic decrease in joint pain and inflammation. Rheumatoid Arthritis (RA) occurs when the immune system incorrectly attacks the body’s tissues, eventually leading to joint deformities, bone erosion and intense pain due to the breakdown of the lining of the joint. Typical treatments for RA involve anti-inflammatory medications, or surgery to repair the joints. However, both types of treatments involve severe side effects and are not guaranteed to work. The stem cell treatment sighted in the case study holds the potential to radically upend current practices and create a new standard of care for this widespread disorder.
In recent clinical trials, researchers at the National University of Ireland Galway have successfully utilized adult stem cells to treat patients with osteoarthritis. The treatment involves recovering the patients’ own [autologous] stem cells and then injecting the stem cells into cartilage to stimulate the regeneration of lost tissue.
Topics: osteoporosis, Fingers, Phase III, Bone loss, Joints, knee replacement, clinical trials, Bone, Debilitating Diseases, Arthritis, Stemcells, Feet, Rheumatoid Arthritis, Hip replacement, Knee, hip, autologousstemcells, cartilage, Cartilage degradation, stemsaveblog
In a novel use of stem cells, scientists at Rockefeller University and The Scripps Research Institute have created what they are referring to as a ‘humanized mouse’, which responds to diseases as a human would. The creation of mice that react to disease and potential treatments the way humans would will significantly reduce the cost, and speed the process, of developing treatments for a wide variety of disease. “We believe this will improve drug discovery because the reactions we observed were authentic human reactions,” says Dr. Harris Perlman of Northwestern University Feinberg School of Medicine. Some of the diseases researchers are using these modified mice to develop treatments for are Rheumatoid Arthritis (RA) – an affliction that affects 70 million people (worldwide) and the Hepatitis C Virus (HCV) which affects 130 million people worldwide.