Researchers at the University of California Irvine, in collaboration with the Barcelona Institute of Science and Technology, have found that consuming a low-calorie diet can prompt the body’s stem cells to remain active and repair age-related wear and tear more efficiently. A low-calorie intake has shown to maintain a youthful circadian rhythm, or biological clock, which is known to regulate and direct stem cell function toward either maintaining homeostasis (equilibrium in the body) or active repair. As we age, our bodies allocate stem cells for various purposes and these cells lose their potency from lack of action, but the reduction in caloric intake reinvigorates these stem cells. In an animal model, researchers found that older stem cells use energy less efficiently compared to younger cells. However, reducing the caloric intake allowed the older cells to reset their biological rhythm, which allowed them to process energy as efficiently as younger cells and regain their youthful potency to make repairs, rather than just maintain the body.