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Stem Cell Infused Lungs Show Promise in Addressing Donor Lung Shortage

Posted by davids@stemsave.com on Jul 25, 2018 1:19:00 PM

 

Researchers at the University of Texas Medical Branch are using autologous (the patient’s own) stem cells to successfully transplant entire lungs without the risk of rejection. In animal models, researchers obtained a lung from a donor and removed all blood and cells, leaving a lung scaffold. Then, they obtained autologous lung stem cells from the subject and seeded the lung scaffold so that the lung would be repopulated. This created a brand new lung for transplantation, comprised of cells that would not be rejected because they are the patient’s own. When implanted back into the body, the engineered lungs were able to grow and vascularize with no additional treatments or infusions. This protocol could potentially be expanded to provide life-saving organs for hundreds of thousands of patients waiting for organ transplants, which, besides the obvious shortage, still pose a risk of immune rejection.

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Topics: regenerative medicine, stem cells, donor organs, organs from stem cells

Stem Cell Grown “Alzheimer’s in a Dish” Sheds Light on the Disease

Posted by anna@stemsave.com on Jul 19, 2018 4:05:00 PM

Researchers at the Massachusetts General Hospital are advancing Alzheimer’s research by creating lab grown models of affected neurons, which will allow for a vastly improved and nuanced understanding of the inner-workings of Alzheimer’s. Alzheimer’s is a neurological disorder that is difficult to diagnose and currently, can only be confirmed during a post-mortem autopsy, which usually reveals the neural inflammation that is believed to be the cause of most of the symptoms leading to the ultimate loss of memory and basic skills. Using stem cells, the researchers were able to grow neurons that exhibit both neuroinflammation and the indicative tangles and plaques of Alzheimer’s. This major breakthrough should enable the development of more targeted, effective treatments - and possibly a cure for Alzheimer’s, which currently affects millions of people worldwide and has no effective treatment options.

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Topics: Alzheimer's disease, treating Alzheimer's, stem cells, neurological treatments, neurological disorders

Today’s Menu Special:  Stem Cells

Posted by Kelsey StemSave on Mar 17, 2017 3:48:24 PM

 

Bay area food technology startup Memphis Meats has grown real-tasting chicken meat, without ever raising a single chicken. Companies are capitalizing on the technology of using stem cells to grow meat tissue, producing meat that bypasses farms, going straight from lab to table. This innovation not only proves more environmentally friendly, but also cuts the costs of feeding and waste disposal associated with raising livestock and poultry, but incorporates stem cells in a novel and unconventional way.

 

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Topics: stem cells, tissue regeneration, growing meat in a lab

Boning Up With Stem Cells

Posted by barb@stemsave.com on Jan 26, 2017 5:00:00 PM

Researchers at South Korea’s Ulsan National Institute of Science and Technology have developed a new scaffolding technique that speeds up stem cell differentiation for bone formation. Utilizing carbon nitride sheets infused with stem cells, the researchers were able to regenerate bone. The carbon nitride sheets possessed photocatalytic properties, which facilitated bone growth. This study marks an important advancement in treatments for bone fractures and periodontal disease.

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Topics: osteoporosis, bone scaffolding, bone fracture, regenerative medicine, stem cells

Building a Heart With Stem Cells

Posted by hunter@stemsave.com on Jan 3, 2017 3:00:00 PM

Researchers at Penn State University, led by Xiaojun Lance Lian, have developed a method to regenerate the surface of a human heart utilizing stem cells. Prior to this advance, researchers could only differentiate stem cells into the middle layer of the heart [myocardium].  By activating the Wnt pathway the researchers were able to direct the stem cells to become the outside layer of the heart [epicardium], bringing researchers one step closer to regenerating an entire heart wall.

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Topics: regenerative medicine, stem cells, heart regeneration, epicardium, heart repair

Clinical Trial for RP Patients Completes Patient Enrollment

Posted by davids@stemsave.com on Dec 13, 2016 3:00:00 PM

California’s Institute for Regenerative Medicine (CIRM) has announced the completion of patient enrollment in a study testing a stem cell derived therapy for retinitis pigmentosa (RP) patients. The treatment involves injecting human retinal progenitor cells into the damaged area of the retina to improve vision. These progenitor cells could either replace the damaged photoreceptors in the eye, or prevent them from being destroyed.

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Topics: clinical trials, Retinitis Pigmentosa, regenerative medicine, stem cells

The 12th Annual World Stem Cell Summit

Posted by devin@stemsave.com on Dec 8, 2016 3:15:32 PM

The Regenerative Medicine Foundation presents the 12th annual World Stem Cell Summit (WSCS) in West Palm Beach, Florida. The WSCS is the largest interdisciplinary stem cell meeting, uniting researchers, funders, and patients from around the world to share the latest medical breakthroughs and discoveries. Embedded within the WSCS is the RegMed Capital Conference, bringing together scientific innovators and investors interested in regenerative medicine and related technologies. The events are broadcasting live from December 6th to December 9th at worlstemcellsummit.com.

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Topics: World Stem Cell Summit, regenerative medicine, stem cells, The Regenerative Medicine Foundation, RegMed Capital Conference

Stem Cells Used to Counteract Side Effects of Chemotherapy

Posted by barb@stemsave.com on Dec 7, 2016 7:10:19 PM

Professor Lars Nielson and his team at the University of Queensland’s Australian Institute for Bioengineering and Nanotechnology are utilizing stem cells to develop a treatment for patients at risk for chemotherapy-induced neutropenia (CIN). Neutropenia is caused by the lack of white blood cells. By differentiating stem cells into white blood cells, the treatment reduces the ‘risk’ period of infection and fever following chemotherapy.

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Topics: regenerative therapies, white blood cells, Umbilical cord blood, stem cells, chemically-induced neutropenia

Dental Stem Cells Advance Understanding of Autism

Posted by anna@stemsave.com on Dec 5, 2016 4:31:11 PM

 

Neurobiologists are utilizing dental stem cells from the pulp of baby teeth to study Autism Spectrum Disorder (ASD). Dental stem cells are very plastic stem cells [they can be differentiated into many types of tissue] derived from the neural crest during early embryonic development.

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Topics: dental pulp, autism, regenerative medicine, stem cells, cell-reprogramming, Autism Spectrum Disorder

Turkeys Catch a Break

Posted by davids@stemsave.com on Dec 2, 2016 11:33:33 AM

Professor Paul Mozdziak and his team at North Carolina State University are growing turkey breast meat from stem cells. By manipulating stem cells into muscle fibers and cultivating them in a “warm broth” of amino acids and glucose, the cells are able to grow into turkey meat. The stem cells are activated to produce protein and fat cells, which add flavor and succulence to the meat, making it very similar to traditional meat.

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Topics: stem cells, cell culturing, muscle fibers, regenerative treatments, cultured poultry

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AAOMS - American Association of Oral and Maxillofacial Surgeons

 

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