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Treating Type I Diabetes with Stem Cells

Posted by maxi@stemsave.com on Jan 8, 2018 1:21:38 PM

Researchers at Cornell University are working on a stem cell-infused implant that could cure insulin deficiency for diabetics. Type I diabetes results from inadequate or malfunctioning insulin-producing beta cells in the islets of the pancreas, as well as an autoimmune response that attacks the body's insulin-producing cells. This treatment utilizes stem cells and directs them to differentiate into these cells. As opposed to daily insulin injections, the treatment is designed to provide a long-term solution that eliminates the need to constantly monitor blood sugar. It utilizes a naturally derived hydrogel to create a thread packed with stem cells induced to become pancreatic islets which is then implanted into the abdomen. Additionally, the treatment addresses what no other current treatment addresses: the body’s immune system attacking the insulin-producing cells. Encasing the cells protects them from the autoimmune response, increasing their efficacy and lifespan. 

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Topics: Type-1 Diabetes, stem cell treatments, regenerative medicine, stem cell diabetes treatment, pancreatic islet cell regeneration, stem cell implant

Type 1 Diabetes Reversed by Integrating Mesenchymal Stem Cells.

Posted by devin@stemsave.com on Feb 12, 2015 5:30:48 AM

MSCs and HCELL molecules track down islet cells and reverse inflammation.

According to a recently published study from the Brigham and Woman’s Hospital, mesenchymal stem cells [MSCs] have the ability to reverse type I diabetes by suppressing the auto-immune attack of islet cells. Although the MSCs cannot be directly injected into the pancreas, the researchers utilized the surface adhesion molecule HCELL to hone the stem cells in on the inflamed islets, allowing them to normalize blood sugar levels without the use of insulin.

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Topics: stemsaveblog, Diabetes, Type-1 Diabetes, Debilitating Diseases, Stemcells, autologousstemcells

Type 1 Diabetes Treatment Advance Utilizes Mesenchymal Stem Cells

Posted by devin@stemsave.com on Sep 13, 2014 6:18:57 AM

The transplantation of adult stem cells into a Type-1 Diabetes animal model has revealed the importance of blood vessels in pancreatic beta cell regeneration.

Researchers led by Dr. Habib Zaghouani from the University of Missouri have developed a potential cure to Type 1 Diabetes by utilizing mesenchymal stem cells [MSCs]. Although researchers anticipated that the MSCs would differentiate into new insulin producing pancreatic beta cells, they discovered that the stem cells fulfilled the more critical function of repairing damaged blood vessels, which in turn facilitated the regeneration of insulin producing pancreatic beta cells and the distribution of insulin across the body.

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Topics: stemsaveblog, Diabetes, Type-1 Diabetes, Debilitating Diseases, Stemcells, Bile duct, Blood vessel

Type 1 Diabetes Treatment Utilizes Stem Cells to Regenerate Pancreatic Beta Cells

Posted by hunter@stemsave.com on Mar 27, 2014 8:35:07 AM

Stem cells have been differentiated into pancreatic beta cells, providing a potential treatment for Type 1 Diabetes.

Researchers from the Gladstone Institutes have developed a potential treatment for Type 1 diabetes by differentiating stem cells into insulin-producing pancreatic beta cells. These new cells, when transplanted into animal models, lowered abnormally high glucose levels down to a more healthy level in just one week.

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Topics: stemsaveblog, Diabetes, Type-1 Diabetes, clinical trials, Debilitating Diseases, Stemcells, autologousstemcells

Wall Street Journal Reports on Stem Cells in Umbilical Cord Blood

Posted by anna@stemsave.com on Jan 13, 2014 10:05:38 AM

Saving stem cells in cord blood ensures access to emerging regenerative therapies.

As reported by the Wall Street Journal, adult stem cell therapies are advancing rapidly; with researchers utilizing stem cells to treat an expanding range of disease, trauma and injury. The article highlights the increasing use of cord blood to treat a variety of ailments such as; Cerebral Palsy, Traumatic Brain Injury and immune deficiencies such as diabetes.

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Topics: traumatic brain injuries, multiple sclerosis, stemsaveblog, Acute Myocardial Infarction, Type-1 Diabetes, clinical trials, Debilitating Diseases, Stemcells, autologousstemcells, heart disease

Stem Cell Diabetes Treatment Option Advances

Posted by devin@stemsave.com on Aug 3, 2013 9:26:33 AM

In an early stage study recently carried out by the Institute of Kidney Diseases and Research Center (IKDRC), a treatment developed by the IKDRC utilizing Insulin Secreting Cells (ISC), derived from the patient’s own mesenchymal stem cells, shows that the need for insulin doses decreased by an average of 50% when the ISCs were implanted in patients.

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Topics: stemsaveblog, Diabetes, Type-1 Diabetes, Stemcells, autologousstemcells, dentalstemcells, dental pulp stem cells

Stem Cell Treatment for Type-1 Diabetes Advances

Posted by barb@stemsave.com on Jun 14, 2013 9:16:22 AM

Millions of individuals around the world suffer from type-1 diabetes, three million in the US alone. Researchers at the University of Missouri, led by Dr. Habib Zaghouani, have developed a two pronged approach to curing the disease: they modulate the immune system with a drug that stops it from attacking the pancreas and use stem cells to regenerate and rebuild the insulin producing pancreatic beta cells.

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Topics: stemsaveblog, Diabetes, Type-1 Diabetes, Stemcells

Researchers Advance Use of Stem Cell Treatments to Develop Potential Cure for Type 1 Diabetes

Posted by hunter@stemsave.com on Jun 4, 2012 7:35:14 PM

In a demonstration of the expanded use of stem cells in novel ways, researchers at the City of Hope Medical Research Center in Duarte, California, have developed a treatment approach that may effectively cure Type 1 diabetes. In this study, researchers utilized stem cells to both initiate regeneration of pancreatic β cells as well moderate the immune system to prevent the destruction of the pancreas.

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Topics: stemsaveblog, Type-1 Diabetes, bank dental stem cells, pancreas, pancreatic β cells, bank stem cells, City Hope Medical Research Center

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