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Type 2 Diabetes Mellitus - Stem Cell Clinical Trials

Posted by devin@stemsave.com on Dec 19, 2017 4:45:00 PM

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In several clinical and animal studies, researchers are utilizing mesenchymal stem cells (MSCs) to treat Type II Diabetes Mellitus (T2DM). Type 2 Diabetes affects approximately 415 million people worldwide, with diabetes mellitus (DM) further exacerbating diabetes’ adverse health effects. Symptoms of DM are caused by both a lack of insulin, as-well-as an intolerance to the scarce amount of insulin that is produced by the pancreatic islet cells. DM is typically a precursor to ischemic heart disease, stroke, blindness and chronic kidney disease with no effective treatments currently available to prevent these complications. With previous treatments using donated organs and insulin producing cells proving unsuccessful, MSCs are emerging as an extremely effective tool to restore normal function to the pancreatic islet cells and alleviate the other symptoms of DM. MSCs (the same type of stem cells that are found in teeth) not only normalize natural insulin levels, but also help ameliorate insulin resistance in the body’s tissues by creating a favorable microenvironment.

In phase I and II clinical trials, as many as 75% of patients were able to either decrease or discontinue their supplemental insulin injections. While the effects of the MSC injections [in current clinical trials] have tended to fade after the first year, the injections are proving effective at reversing the progression of DM and its subsequent complications hence, additional clinical trials are under way to determine the optimum treatment protocols to achieve longer term effectiveness of MSC base treatments.

 With more clinical trials underway, this advancement in bioengineering will accelerate the use of MSCs and broaden their application to treat a wider variety of symptoms resulting from diabetic complications. By banking their own valuable stem cells, families can ensure that they will have access to these emerging therapies in the near future. To learn more about banking stem cells, please visit StemSave or call 877-783- 6728 (877-StemSave) today.

 

The Future of Regenerative Medicine is Now™

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Topics: type 2 diabetes, diabetes mellitus, stem cell diabetes treatment, mesenchymal stem cells, pancreatic beta cells, pancreatic islet cell regeneration

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AAOMS - American Association of Oral and Maxillofacial Surgeons

 

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