Researchers at the Wyss Institute and Harvard School of Engineering and Applied Sciences have developed a self-shrinking gel that, when loaded with mesenchymal stem cells [MSCs], stimulates their ability to differentiate into teeth, bones, and organs in vivo [in the patient’s body]. The gel is designed to spontaneously compress at 37°C [the temperature of the human body], which places the physical pressure required to trigger the stem cells’ proliferative properties while inside the patient’s body.
This novel use of bio-gel and MScs was inspired by the process of embryonic induction, in which MSCs are compressed to send each other the necessary signals for organ formation. Although the in vivo formation of teeth is a significant advance all on its own, lead authors Basma Hashmi and Don Ingber believe that stem cells can be used to generate a multitude of organs for patients suffering from a variety of traumas, injuries, and diseases.
Mesenchymal stem cells have the unique capacity to regenerate a multitude of different types of tissues – such as neurons, insulin producing pancreatic beta cells, bone, cartilage, and cardiomyocites amongst them. To learn more about the value of preserving your own MSCs for use in future regenerative therapies and how to bank your own stem cells through a non-invasive and affordable method by recovering your dental pulp stem cells, visit StemSave or call 877-783-6728 (877-StemSave) today.
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