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In with a BAM – Stem Cells Advance Bladder Regeneration

Posted by on Jan 6, 2015 4:56:01 AM

The bladder acellular matrix is a housing of connective tissue that provides structural support for the functional cells of the bladder

New research from McGill University has shown that the bladder acellular matrix [BAM], or the external structure of connective tissue and growth factors that house the cellular components of the bladder, can serve as a scaffolding unit for mesenchymal stem cells [MSCs] to regenerate healthy bladder tissue. The stem cells receive growth factors from the BAM, which direct them to differentiate into new bladder cells that, when transplanted into an animal model, exhibit nearly 100% normal bladder capacity and function.

Although stem cells have been integral for bladder engineering for some time, the use of the BAM in conjunction with MSCs marks a significant advance in bladder regeneration. By providing the proper structure and microenvironment of the bladder, the BAM can herald substantial progress in the development of organ replacement technologies that utilize MSCs to treat patients with malformations, traumas, and diseases of the bladder.

As regenerative engineering progresses, we believe the best stem cells to use in emerging treatments will be the patient’s own [autologous stem cells] as this negates the need to find a suitable donor and eliminates the chances of rejection of the transplanted tissue. To learn more about banking your own valuable stem cells to insure your family’s future health, visit StemSave or call 877-783-6728 (877-StemSave) today.



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Topics: stemsaveblog, Debilitating Diseases, Stemcells, Bladder Diseases, autologousstemcells, Bladder


AAOMS - American Association of Oral and Maxillofacial Surgeons


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