Researchers at the University Hospital Niño Jesus in Madrid, Spain, are conducting a clinical trial to determine the safety and efficacy of treating cerebral palsy patients with hematopoietic stem cells from cord blood, as well as mesenchymal stem cells [MSCs] from umbilical cord tissue. The scientists will compare the two types of autologous [the patient’s own] stem cells in their effectiveness regarding immune-regulation, anti-inflammatory activity, and stimulation of brain tissue regeneration.
This clinical trial, the first to utilize MSCs from cord blood tissue, can represent a new step towards determining the most effective method for treating cerebral palsy. According to Frederic Amar, CEO of the trial’s sponsor ESPERITE, "The clinical trial…will take a step toward development of new interventions in pediatric neurology and will provide better explanations of the mechanisms responsible for therapeutic effects of stem cells expanded ex-vivo for application in personalized regenerative medicine."
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