Researchers at University of California San Francisco (UCSF) have created insulin producing cells in vitro that successfully produced insulin in vivo for Type I Diabetes patients. Type I diabetics experience an autoimmune disorder which attacks and destroys the body’s insulin-producing beta cells. These patients have to take continuous insulin injections and closely and constantly monitor their blood sugar levels, since extremely high or low blood sugar levels cause diabetic ketoacidosis or hyperglycemic shock, leading to coma and death. Though diabetes is currently manageable, patients must be constantly vigilant since their bodies’ inability to regulate blood sugar often leads to other systemic diseases such as blood vessel damage, neuropathy and nephropathy, just to name a few. The study from USCF involved directing human pancreatic stem cells to become insulin-producing islets cells in the lab. In an animal model, the cells were then implanted back into the body and were shown to produce insulin in response to blood sugar spikes. Additionally, the islets produced other essential hormones for blood sugar regulation, fully resembling normal pancreatic islets.
Since diabetes affects millions of individuals around the world, finding a permanent solution that does not require constant monitoring is becoming more imperative. “Current therapeutics like insulin injections only treat the symptoms of the disease… Our work points to several exciting avenues to finally finding a cure,” says Gopika Nair, PhD and lead researcher on the study.
As treatments emerge, we believe the best stem cells to use will be the patient’s own [autologous stem cells] as this negates the need to find a suitable donor and eliminates the chances of rejection of the transplanted tissue. To learn how to bank your own valuable stem cells to insure your future health, visit www.StemSave.com or call 877-783-6728 (877-StemSave) today.
The Future of Regenerative Medicine is Now™
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