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Dental Pulp Stem Cells Treat Stress Urinary Incontinence

Posted by on Sep 17, 2019 11:30:00 AM

Picture1-7Researchers are using human dental pulp stem cells (DPSCs) to treat stress urinary incontinence (SUI), an involuntary bladder leakage due to an increase in pressure or damage to the urethral sphincter. Treatments for this condition typically target the symptoms rather than the cause of SUI. As this condition affects over 200 million people worldwide, developing a viable treatment option, as opposed to symptom control, will improve the quality of life of millions of people. Additionally, since this study utilizes human DPSCs, patients who have banked their dental stem cells will have access to this treatment option without the need to find a suitable donor match or assume the risk of rejection.

In an animal model, the DPSCs were initially differentiated into muscle support cells and then injected into the defective urethral sphincter. Four weeks following the application, the DPSCs progressed into a myogenic lineage, which developed into muscle cells to support the damaged sphincter, while also facilitating the regeneration of the damaged nerve that causes urinary incontinence.

With clinical trials soon underway, this advancement in bioengineering will accelerate this trend and broaden applications to treat a wider variety of disease, trauma and injury. By banking their own valuable stem cells, families can ensure that they will have access to these emerging therapies soon. To learn more about banking stem cells, please visit StemSave or call 877-783- 6728 (877-StemSave) today.


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Topics: dental pulp stem cells


AAOMS - American Association of Oral and Maxillofacial Surgeons


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