Researchers in Japan have made headway in bringing tooth regeneration to clinical trials. This major breakthrough involved utilizing both epithelial and dental stem cells to create tooth buds that were then implanted into the jaw bone. The ‘tooth buds’ grew into fully functional adult teeth in the span of 5 months. In this animal model, the researchers first used a biological scaffold and seeded the epithelial and dental stem cells to create a tooth bud, which acts like a seed for a new tooth to grow. This is similar to the tooth buds that children have below their deciduous teeth (baby teeth). The study showed that the regenerated tooth maintained both biological form and function, including a response to orthodontic force that caused the biological implanted tooth to move in the same way a normal tooth would.
While the study is still in the animal testing stages, these promising results bring researchers one step closer to foregoing artificial dental implants in favor of tooth regeneration for missing teeth. As the study was conducted on canines, it demonstrated a progression in the success of the research to create biological teeth on more complex organisms that are more physiologically similar to humans than rats or mice. This study, among others, affirms the general trend in regenerative medicine and, dentistry in particular, as researchers hope to provide better, more personalized alternatives to the current standard of care.
As regenerative engineering progresses, we believe the best stem cells to use in emerging treatments will be the patient’s own [autologous stem cells] as this negates the need to find a suitable donor and eliminates the chances of rejection of the transplanted tissue. To learn more about banking your own valuable stem cells to insure your family’s future health, visit StemSave or call 877-783-6728 (877-StemSave) today.
The Future of Regenerative Medicine is Now™
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