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Recruiting Stem Cells to Combat Gum and Bone Loss Due to Periodontal Disease

Posted by on Mar 15, 2019 3:10:00 PM

images-17Researchers at the American Chemical Society (ACS) have developed a biopolymer that would be implanted into an affected gum line to recruit stem cells and restore the damage caused by periodontal disease. With the Centers for Disease Control predicting that nearly half of all Americans will be affected by periodontal disease during their lifetimes,  the new regenerative treatment technique would save healthy teeth, avoid prolonged and costly treatments and provide dentists with a more effective and less invasive treatment option for their patients.

The biopolymer membrane developed by the ACS serves as structural support for the stem cells during the time of treatment, as well as recruiting the necessary minerals for bone regeneration. Additionally, the researchers coated the biopolymer membrane with polydopamine (PDA), which recruited and enabled stem cells to adhere to the polymer surface and regenerate lost gum tissue. The PDA coating also attracted calcium and phosphate ions, which helped restore lost bone. In an animal model, the affected bone and periodontal tissue regenerated to normal levels, and the polymer was absorbed by the body, eliminating the need for further intervention previously required to remove synthetic polymers.

In addition to an emerging stem cell therapy to treat periodontal disease, advances in regenerative therapies to regrow and repair teeth and replace lost bone puts dentistry squarely at the forefront of regenerative medicine. With the demonstrated proliferation and differentiation properties of dental stem cells, dentistry can provide family’s with the opportunity to participate in future regenerative therapies [utilizing their own stem cells] by banking the stem cells found in teeth during routine dental procedures.  To learn more about stem cell banking, visit or call 877-783-6728 (877-StemSave) today.


The Future of Regenerative Medicine is Now™

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Topics: dental stem cells, bone regeneration, stem cell rejuvenation, periodontal disease


AAOMS - American Association of Oral and Maxillofacial Surgeons


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