Researchers at UT Southwestern Medical Center have identified a gene that directs the production of a stem cell factor (SCF) and a protein, which are both essential for hair growth and pigmentation. Stem cells are concentrated in the skin around hair follicles, and when both the protein and the SCF are active, they move up from the bulb of the follicles to produce pigmented hairs. The genes responsible for the production of the KROX20 protein and the SCF were discovered by working backwards, turning off the gene and observing, in mice subjects, that no pigmentation was present in the hairs and that the subjects became bald.
By directing the stem cells in the hair follicle to produce both the KROX20 protein and the stem cell factor (SCF), a non-invasive treatment for baldness may soon be possible. “With this knowledge, we hope in the future to create a topical compound or to safely deliver the necessary gene to hair follicles to correct these cosmetic problems,” says Dr. Lee, associate professor of dermatology at the Harold C. Simmons Cancer Center at UT Southwestern.
As treatments emerge, we believe the best stem cells to use will be the patient’s own [autologous stem cells] as this negates the need to find a suitable donor and eliminates the chances of rejection of the transplanted tissue. To learn how to bank your own valuable stem cells to insure your future health, visit www.StemSave.com or call 877-783-6728 (877-StemSave) today.
The Future of Regenerative Medicine is Now™
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