Researchers at the University of Bristol, led by Dr. Adam Perriman, have hypothesized that using stem cells that are “welded together” may be the key to healing chronic wounds that often result from diabetes and other afflictions. The research involves using mesenchymal stem cells (the same type of stem cells found in teeth) and modifying their membranes so that the cells adhere to one another.
The cells were modified with a naturally occurring enzyme - thrombin, which is used by the body to naturally induce clotting. When these cells were placed in a solution with additional proteins, the cells adhered to one another and created a 3D biological gel. Since mesenchymal stem cells can differentiate into connective tissue, this biological gel could be applied to chronic wounds and the connected network of cells can both physically cover the wound and eventually become part of the patient’s skin. According to Dr. Perriman, "One of the biggest challenges in cell therapies is the need to protect the cells from aggressive environments after transplantation. We have developed a completely new technology that allows cells to grow their own artificial extracellular matrix, enabling cells to protect themselves and allowing them to thrive after transplantation."
Advances in stem cell based regenerative treatments are creating more effective treatment options for patients suffering from a wide variety of disease, trauma and injury. To learn more about stem cells, and how families can bank their own valuable stem cells by recovering the very powerful dental pulp stem cells during routine dental procedures; such as wisdom teeth extractions or the during the loss of baby teeth, visit StemSave or call 877-783-6728 (877-StemSave) today.
The Future of Regenerative Medicine is Now™
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