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Stem Cell Bone Differentiation

Posted by on Dec 14, 2015 4:08:00 PM

Researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences and The Wyss Institute for Biologically Inspired Engineering have developed a new, more precise way to control the differentiation of stem cells into bone cells.

The viscoelasticity of living tissue was mimicked by creating hydrogels with different stress relaxation responses. Not only did increased stress relaxation dramatically increase early osteogenic differentiation but those cells continued to grow as bone cells weeks after their initial differentiation and formed an interconnected mineralized matrix rich in collagen, key structural features of bone.

“This work both provides new insight into the biology of regeneration, and is allowing us to design materials that actively promote tissue regeneration,” said Mooney, a coauthor of the paper and faculty member of the Wyss Institute.

As personalized regenerative medicine advances, autologous stem cells will become an invaluable resource to families and individuals who seek to ensure that they will have access to the best in medical care should the need for it arise. One of the most convenient and affordable sources for recovering and banking your own stem cells is dental stem cells. To learn more about how to bank dental stem cells for use in future therapies and treatments, visit StemSave or call 877-783-6728 (877-StemSave) today.


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Topics: stemsaveblog, hydrogel, stem cell differentiation, Regenerative Biology and Tissue Engineering, osteogenesis, collagen


AAOMS - American Association of Oral and Maxillofacial Surgeons


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