Researchers at Texas A&M University have created nanoparticles that could ameliorate and prolong the effects of stem cells on cartilage regeneration in osteoarthritis. Osteoarthritis is an affliction that results from the degradation of the cartilage between joints, which serves to lubricate and prevent friction between bones. Symptoms often include joint swelling and pain, and decreased range of motion, which causes the areas around the joints to well and solidify. A treatment for osteoarthritis is vital since aging populations show an increasing prevalence of the affliction, and a stem cell treatment could contribute to longer healthspans.
A case study utilizing a patient’s own stem cells to treat rheumatoid arthritis demonstrated a drastic decrease in joint pain and inflammation. Rheumatoid Arthritis (RA) occurs when the immune system incorrectly attacks the body’s tissues, eventually leading to joint deformities, bone erosion and intense pain due to the breakdown of the lining of the joint. Typical treatments for RA involve anti-inflammatory medications, or surgery to repair the joints. However, both types of treatments involve severe side effects and are not guaranteed to work. The stem cell treatment sighted in the case study holds the potential to radically upend current practices and create a new standard of care for this widespread disorder.
Dr. Farid Saleh at the Erhlich Animal Hospital and Arthritis Therapy Center in Tampa, Florida is utilizing innovative stem cell treatments to improve the lives of pets with degenerative disorders. Just like people, animals can suffer from ailments such as arthritis, and this leads to difficulty moving, which significantly decreases the animal’s quality of life. The Hospital’s application of stem cell treatments in animals could disseminate throughout the medical industry, making treatments more readily accessible to people, in addition to bettering the lives of everyone’s beloved pets.
Dr. John Szivek, a researcher from the University of Arizona, is growing cartilage from stem cells. The process would utilize the patient’s own stem cells. The grown cartilage would be used to repair arthritic related damage, both small and large, and may one day eliminate the need to put plastics and/or metals in patient’s joints.