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Autism Treated With Stem Cells

Posted by barb@stemsave.com on Jan 14, 2019 2:58:00 PM

Researchers at Duke University have utilized autologous (the patient’s own) stem cell infusions to promote increased connectivity in the brain that allowed for improved communication and language abilities in children with Autism Spectrum Disorder (ASD). The stem cells used in the trial were the patients’ own cord blood stem cells, which were banked at birth and played a key role in alleviating the symptoms of ASD in these patients. The Phase I Clinical Trial utilized the autologous stem cells in i.v. infusions that were meant to deliver the cells to the white matter, which is one of the brain tissues that differs developmentally between individuals with and without ASD. Additionally, the study targeted the neuroinflammation present in individuals with ASD.

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Topics: autism and stem cells, autologous stem cells, Autism Spectrum Disorder, stem cell treatment

Stem Cells Shed Light on Autism Spectrum Disorder

Posted by devin@stemsave.com on Dec 29, 2018 1:51:00 PM

Researchers at the Salk Institute have used stem cells to understand the changes in neural development for individuals with Autism Spectrum Disorder (ASD). This study has uncovered the first measurable changes in neuronal development of individuals with ASD, which is a major step toward understanding the disorder and ameliorating current therapies. The research found that by allowing the stem cells to differentiate into neurons, several developmental steps differed in cells from individuals with ASD compared to the control group. This led researchers to the conclusion that changes occur much earlier in neuronal development, since cells from individuals with ASD turn on their genes for neuronal development much earlier and the neurons grew faster compared to controls.

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Topics: autism and stem cells, stem cell therapy, stem cell research, Autism Spectrum Disorder

Autism Spectrum Disorder Ameliorated with a Patient’s Own Stem Cells

Posted by barb@stemsave.com on Feb 15, 2018 5:39:03 PM

Families choosing to bank their stem cells – usually in the form of cord blood and/or dental pulp stem cells, typically view their decision as “biological insurance.” A Phase II clinical trial is investigating the safety and efficacy of autologous [the patient’s own] cord blood stem cells to treat children with behavioral and social difficulties associated with Autism Spectrum Disorder (ASD). In a clear demonstration of the value of banking your own stem cells, only families that chose to bank their children’s cord blood were qualified to participate in the study. 

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Topics: autism and stem cells, dental stem cell banking, Umbilical cord blood, regenerative medicine, Autism Spectrum Disorder, stem cell banking

Dental Stem Cells Provide Insight into Autism

Posted by anna@stemsave.com on Nov 11, 2017 8:45:00 AM

Dr. Patricia Braga and her team at the University of Sao Paolo, in collaboration with Alysson Muotri, professor of pediatrics and cellular and molecular medicine at UC San Diego, are using dental stem cells from donated baby teeth to grow neurons and examine the role of astrocytes in the expression of Autistic traits such as language impairment, repetitive behaviors and sleeping difficulties. Dr. Braga has used dental pulp stem cells from two groups of  patients - children with Autism and a non-autistic control group, and directed their stem cells to differentiate into brain cells in vitro. When allowed to grow, the stem cells developed into clusters that contained the star-shaped brain cells called astrocytes, as well as fully grown neurons. Upon closer inspection, the astrocytes and neurons from children with Autism showed significant functional differences compared to the control group cells. Autistic astrocytes release excessive amounts of an inflammatory molecule called interleukin-6 (or IL6), which, in concentrated amounts, can harm nearby neurons and hinder their functionality. Additionally, the neurons from Autistic children were found to fire less frequently, form fewer synapses (connections with other neurons) and release less glutamate, which is used to excite surrounding neurons and transmit signals.

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Topics: autism and stem cells, dental stem cell, autologous dental pulp stem cells, regenerative medicine, Autism Spectrum Disorder

Dental Stem Cells Advance Understanding of Autism

Posted by anna@stemsave.com on Dec 5, 2016 4:31:11 PM

 

Neurobiologists are utilizing dental stem cells from the pulp of baby teeth to study Autism Spectrum Disorder (ASD). Dental stem cells are very plastic stem cells [they can be differentiated into many types of tissue] derived from the neural crest during early embryonic development.

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Topics: dental pulp, autism, regenerative medicine, stem cells, cell-reprogramming, Autism Spectrum Disorder

AAOMS

AAOMS - American Association of Oral and Maxillofacial Surgeons

 

As the industry leader, StemSave is the only stem cell banking service to be designated as an ASI approved program.

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