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Dental Stem Cells Used in Parkinson’s Treatment

Posted by davids@stemsave.com on Feb 4, 2019 11:08:00 AM

Researchers are utilizing vesicles secreted from dental stem cells to treat Parkinson’s Disease (PD). The study utilized these vesicles secreted by stem cells, as they are small and can easily cross the blood-brain barrier to deliver a treatment to the parts of the brain affected by PD. Parkinson’s is a neuro-degenerative disorder that affects the part of the brain that produces a neurotransmitter called dopamine, with symptoms expressing themselves as tremors and limb rigidity, among others. This study demonstrated, in an animal model, that intranasal administration of dental stem cell vesicles had a therapeutic effect by regulating the expression of proteins and preventing dopaminergic neuron death. The results showed a decrease in PD tremors and showed no adverse neurological effects over the progression of the study.

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Topics: parkinsons disease, dental stem cells, mesenchymal stem cells, autologous stem cells, stem cell treatment, regenerative medicine

Alzheimer’s Treated With Stem Cells

Posted by anna@stemsave.com on Jan 21, 2019 10:19:00 AM

In a Phase II clinical trial, researchers are using autologous (the patients’ own) mesenchymal stem cells to treat Alzheimer’s disease. According to the Centers for Disease Control (CDC) 5.7 million Americans are currently suffering from Alzheimer’s [with approximately 5.5 million over the age of 65 and approximately 220k under 65 experiencing early onset Alzheimer’s] with the number expected to triple by 2060. Additionally, the disease is one of the top 10 leading causes of death in U.S. adults; and while incidents of other common ailments like heart disease and cancer are decreasing, Alzheimer’s is on the rise.

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Topics: treating Alzheimer's, Alzheimer's disease, stem cell treatment, autologous stem cells, mesenchymal stem cells, Phase I/II clinical trial

Autism Treated With Stem Cells

Posted by barb@stemsave.com on Jan 14, 2019 2:58:00 PM

Researchers at Duke University have utilized autologous (the patient’s own) stem cell infusions to promote increased connectivity in the brain that allowed for improved communication and language abilities in children with Autism Spectrum Disorder (ASD). The stem cells used in the trial were the patients’ own cord blood stem cells, which were banked at birth and played a key role in alleviating the symptoms of ASD in these patients. The Phase I Clinical Trial utilized the autologous stem cells in i.v. infusions that were meant to deliver the cells to the white matter, which is one of the brain tissues that differs developmentally between individuals with and without ASD. Additionally, the study targeted the neuroinflammation present in individuals with ASD.

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Topics: Autism Spectrum Disorder, autism and stem cells, autologous stem cells, stem cell treatment

Fighting Epilepsy With Stem Cells

Posted by anna@stemsave.com on Nov 29, 2018 12:10:00 PM

Researchers at Texas A&M University are utilizing stem cell injections into the brain to alleviate the most common and severe case of seizures of Temporal Lobe Epilepsy (TLE) in an animal model. The experimental treatment resulted in 70% of the subjects experiencing a reduction in the number of seizures with researchers expecting the number to climb as the research advances. Current treatment of TLE involves treatment with medication [to which 40% of patients do not respond] or, invasive surgery. To eliminate this type of epilepsy, some patients have their entire hippocampus removed, which can lead to disastrous side effects impacting the patient’s mood and memory.  

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Topics: epilepsy, epileptic seizures, stem cell treatment, autologous stem cells

Soccer Star Luis Suarez Scores with Stem Cells

Posted by davids@stemsave.com on Nov 14, 2018 2:29:00 PM

Luis Suarez, a star of FC Barcelona, will undergo a stem cell treatment to alleviate pain in his knee and prevent further injury. Suarez has been dealing with intermittent spurs of pain, and a traumatic crash during a recent match exacerbated his injury and may have sidelined him for several weeks. However, Suarez’s stem cell treatment should have him back on the field in approximately 2-week's-time.

The treatment involves recovering the patient’s own stem cells (in this case mesenchymal stem cells - the same type of stem cells found in teeth), concentrating them and injecting them into the site of the injury to accelerate healing, decrease inflammation and eliminate the need for surgical intervention.

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Topics: stem cell injection, knee injury treatment, chronic pain, professional athlete, sports injuries, mesenchymal stem cells, autologous stem cells

MS Phase II Clinical Trial Launched Using Patient Stem Cells

Posted by devin@stemsave.com on Nov 4, 2018 9:44:00 AM

BrainStorm Cell Therapuetics is currently launching a Phase II clinical trial utilizing mesenchymal stem cells (MSCs) that are cultured to develop into neurological components able to treat progressive multiple sclerosis (MS). The proprietary technology called NurOwn uses a patient’s own (autologous) MSCs that are modified outside of the body and returned to repair and support neurons that are attacked in patients with MS. The stem cells are modified to produce growth factors, which support neurons and enhance differentiation and survival of neural cells.

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Topics: MS, multiple sclerosis treatment, multiple sclerosis, stem cell treatment, autologous stem cells

Rheumatoid Arthritis Stem Cells Treatment

Posted by pamela@stemsave.com on Oct 16, 2018 1:43:00 PM

A case study utilizing a patient’s own stem cells to treat rheumatoid arthritis demonstrated a drastic decrease in joint pain and inflammation. Rheumatoid Arthritis (RA) occurs when the immune system incorrectly attacks the body’s tissues, eventually leading to joint deformities, bone erosion and intense pain due to the breakdown of the lining of the joint. Typical treatments for RA involve anti-inflammatory medications, or surgery to repair the joints. However, both types of treatments involve severe side effects and are not guaranteed to work. The stem cell treatment sighted in the case study holds the potential to radically upend current practices and create a new standard of care for this widespread disorder.

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Topics: Rheumatoid Arthritis, autologous stem cells, stem cell therapy, arthritis treatment, mesenchymal stem cells, autoimmune disease

Stem Cells Used to Repair Cleft Palates in Children

Posted by hunter@stemsave.com on Sep 21, 2018 1:15:00 PM

Researchers at Hospital De San Jose in Colombia have utilized autologous (the patients’ own) stem cells to regenerate bone in children with cleft palates, greatly improving their quality of life by replacing an often arduous, surgically invasive procedure with a stem cell graft.The children partaking in the study were born with cleft palates, which typically require surgery and extensive grafting with bone from elsewhere in the body to create enough bone matter to support future teeth. When the children were born, their parents made the wise decision to bank their children’s powerful cord blood stem cells, which became vital to the success of this later treatment. This groundbreaking study used the patients’ own stem cells and a biological scaffold to allow the stem cells to grow into bone and fill the cleft. The ability to use autologous stem cells posed no risk of rejection to the patients, and in 5 and 10-year follow ups, the patients showed healthy bone development and experienced no adverse effects.

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Topics: cleft palate repair, stem cell graft, investing in future health, stem cell banking, regenerative medicine, bone regeneration, autologous stem cells

Stem Cells Reverse MS in Breakthrough Clinical Trial

Posted by taylor@stemsave.com on Dec 1, 2017 12:30:00 PM

A team of researchers at the Hadassah Medical Center in Israel has developed a unique method of applying a patient’s own stem cells to restore mobility following progressive multiple sclerosis (MS). MS is an autoimmune disorder in which the body attacks its own neurons and affects millions of people worldwide. Severely progressive MS leads to complete loss of limb function, memory problems, seizures, and even systemic organ failure. This groundbreaking, double-blind, Phase II clinical trial successfully administered autologous (the patient’s own) mesenchymal stem cells, which were cultured and expanded to clinically significant numbers, and then applied directly into the spinal fluid. The treatment simultaneously addressed the two problems of MS - inflammatory immune response and the destruction of the outer coating of neurons that allows for quick signal transduction thereby engendering a significant increase in efficacy.

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Topics: MS, multiple sclerosis, multiple sclerosis treatment, autologous stem cells, mesenchymal stem cells, patient's own mesenchymal stem cells

Stem Cells Reverse Paraplegia

Posted by devin@stemsave.com on Nov 29, 2017 4:45:00 PM

Researchers at the Technion-Israel Institute have directed stem cells to differentiate into neurons with the potential to repair spinal damage that causes paralysis in the legs, known as paraplegia. In an animal model, subjects suffering injury to their spinal cords, causing them to lose all mobility and feeling in their hind limbs, were treated with human stem cells cultured to differentiate into support factors that promote neural growth and survival. Three weeks after administering the stem cell treatment, 42% of the subjects began either walking or showing significant improvements in bearing weight on their hind legs. Furthermore, over 75% of the subjects responded to stimulation in their hind legs. When compared to the placebo group that received no stem cells, the results were impressive and demonstrate  the immense potential of utilizing stem cells to restore the neural connections in the spine following a traumatic injury.

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Topics: paraplegia, quadriplegia, stem cell paralysis treatment, adult stem cells, autologous stem cells, regenerative medicine, Paralysis

AAOMS

AAOMS - American Association of Oral and Maxillofacial Surgeons

 

As the industry leader, StemSave is the only stem cell banking service to be designated as an ASI approved program.

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