University of Pennsylvania researchers have utilized dental stem cells from baby teeth to restore injured teeth. The clinical trial involved the use of the patient’s own (autologous) stem cells to treat an injured permanent tooth. The stem cells were obtained from a healthy baby tooth [hence, posed no risk of rejection, since they were the patient’s own], expanded in the lab and implanted into the injured tooth. In follow-ups one year following the procedure, patients in the experimental group regained sensation in the previously injured tooth. The researchers also observed a significant regeneration of dentin, which is the hard part of the tooth, as well as vascularization in the pulp, which led to healthy root development and increased circulation.
A recent study from the Republic of Korea reinforces the knowledge of dental pulp stem cells as a viable source of stem cells for use in many forms of regenerative therapies. Upon isolating a population of mesenchymal stem cells from the dental pulp of third molars, the research team identified pluripotent characteristics in the stem cells as they relate to the extremely important indicators of cell viability such as telomere length, telomerase activity, and reverse transcriptase activity.
Professor Gordana Vunjak-Novakovic, one of StemSave's Scientific Advisers, has just been elected to the prestigious National Academy of Engineering (NAE), one of the highest professional distinctions awarded to an engineer, for her work with bioreactor systems and modeling approaches for tissue engineering and regenerative medicine. She joins only 2,500 engineers around the world.
Topics: stemsaveblog, wisdom teeth, columbia university, wisdom teeth stem cells, dental stem cells, baby teeth stem cells, Stem Save, professor gordona vunjak-novakovic, life sciences, national academy of engineering, banking stem cells, stem cell harvest