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3D Printers Mend Broken Hearts

Posted by hunter@stemsave.com on Apr 22, 2019 4:18:00 PM

Researchers in Tel Aviv have printed the first vascularized heart made from human stem cells. For the first time, researchers successfully printed heart tissue along with the blood vessels necessary for the heart to be operational. In a miniaturized version, the researchers also incorporated the chambers of the heart. The next step is scaling up the size of the printed heart to the size typically found in humans.  Researchers believe a successful scaling up of the process would accelerate parallel efforts to bio-engineer organs in vitro and ameliorate the vast organ shortage, particularly with hearts.

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Topics: dental stem cells, stem cell banking, stem cell 3D printing, stem cell printing

3D Printing Tissues with Stem Cells

Posted by maxi@stemsave.com on Apr 10, 2019 11:47:00 AM

Researchers at UC Berkeley have been working on improving and scaling up and the printing of biomaterials with stem cells. They have developed a unique approach to ‘3D’ bioprinting by incorporating flash freezing into their process. They have improved on current techniques by printing layers of flat tissues [2D] and freezing them until they can be combined into a 3D structure. This technique was developed to overcome one of the major hurdles in scaling up 3D printing: the survival of the printed cells during the lengthy process of printing complex structures. By using 2D layers and flash freezing them before bringing them together to form a 3D organ or tissue structure, the new technique assures the survival of the cells throughout bigger, and more complex organs.

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Topics: dental stem cells, stem cell banking, stem cell printing, 3D printed organs, stem cell grafts

Recruiting Stem Cells to Combat Gum and Bone Loss Due to Periodontal Disease

Posted by devin@stemsave.com on Mar 15, 2019 3:10:00 PM

Researchers at the American Chemical Society (ACS) have developed a biopolymer that would be implanted into an affected gum line to recruit stem cells and restore the damage caused by periodontal disease. With the Centers for Disease Control predicting that nearly half of all Americans will be affected by periodontal disease during their lifetimes,  the new regenerative treatment technique would save healthy teeth, avoid prolonged and costly treatments and provide dentists with a more effective and less invasive treatment option for their patients.

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Topics: dental stem cells, bone regeneration, stem cell rejuvenation, periodontal disease

Dental Stem Cells Used in Parkinson’s Treatment

Posted by davids@stemsave.com on Feb 4, 2019 11:08:00 AM

Researchers are utilizing vesicles secreted from dental stem cells to treat Parkinson’s Disease (PD). The study utilized these vesicles secreted by stem cells, as they are small and can easily cross the blood-brain barrier to deliver a treatment to the parts of the brain affected by PD. Parkinson’s is a neuro-degenerative disorder that affects the part of the brain that produces a neurotransmitter called dopamine, with symptoms expressing themselves as tremors and limb rigidity, among others. This study demonstrated, in an animal model, that intranasal administration of dental stem cell vesicles had a therapeutic effect by regulating the expression of proteins and preventing dopaminergic neuron death. The results showed a decrease in PD tremors and showed no adverse neurological effects over the progression of the study.

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Topics: parkinsons disease, dental stem cells, mesenchymal stem cells, regenerative medicine, autologous stem cells, stem cell treatment

Dental Stem Cell Therapy for Stroke Victims

Posted by davids@stemsave.com on Oct 12, 2017 4:45:00 PM

Researchers at Adelaide University in Australia are conducting research into the application of dental pulp stem cells to treat neurological damage due to stroke. Cell based treatments for the detrimental effects of stroke could improve quality of life by promoting neural regeneration, neuroplasticity, vascularization and immuno-modulation. When an ischemic stroke occurs, a major artery in the brain becomes blocked due to a blood clot, and this deprives part of the brain of nutrients and oxygen. Depending on the length of the block, major parts of the brain can suffer neuronal death causing severe and permanent damage. This damage includes paralysis, vision problems, memory loss and language difficulties. Currently, there are no effective treatments for the effects of stroke, and because dental stem cells are derived from the neural crest during embryonic development, a dental stem cell based treatment shows promise in significantly improving the quality of life for stroke victims.

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Topics: Chronic Ischemic Heart Disease, dental stem cells, mesenchymal stem cells, regenerative medicine, stroke treatments

Dental Stem Cells Used to Regrow Fully Functional Teeth

Posted by anna@stemsave.com on Apr 24, 2017 3:45:00 PM

Researchers in Japan have made headway in bringing tooth regeneration to clinical trials. This major breakthrough involved utilizing both epithelial and dental stem cells to create tooth buds that were then implanted into the jaw bone.  The ‘tooth buds’ grew into fully functional adult teeth in the span of 5 months. In this animal model, the researchers first used a biological scaffold and seeded the epithelial and dental stem cells to create a tooth bud, which acts like a seed for a new tooth to grow. This is similar to the tooth buds that children have below their deciduous teeth (baby teeth). The study showed that the regenerated tooth maintained both biological form and function, including a response to orthodontic force that caused the biological implanted tooth to move in the same way a normal tooth would.

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Topics: deciduous teeth, stem cells from teeth, dental stem cells, regrowing teeth, regenerative medicine

Banking on Baby Teeth

Posted by pamela@stemsave.com on Jul 11, 2016 2:00:00 PM

Author Kali Sakai, reports on banking stem cells from teeth in Parent Map. The daughter of a dentist, Sakai learned about teeth, however she was unaware of the stem cells inside teeth. As Sakai states, “It blew my mind to think that my child’s baby tooth could hold the key to a life-saving treatment in her adulthood”.

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Topics: dental stem cells, hematopoietic stem cells, Umbilical cord blood, banking stem cells, mesenchymal stem cells, biological insurance, parent map, baby teeth

Spinal Cord Injury Treatment From Stem Cells

Posted by maxi@stemsave.com on Jul 8, 2016 4:30:00 PM

Researchers at the Sri Ramachandra University (SRU) in Chennai have differentiated stem cells from human gum [gingival] tissue into neurons. Following their success, Dr. R. Suresh and research scholars S. Rajasekharan and M. G. Dinesh hope to develop methodologies to utilize the differentiated nerve cells to treat spinal cord injuries.

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Topics: dental stem cells, spinal cord injury, stem cell treatments, nerve cells, grow stem cells, stem save blog, human gum tissue, neural crest

StemSave Chief Scientific Advisor Dr. Jeremy Mao, Distinctive Voices Lecturer at The Beckman Center of the National Academy of Sciences, Discusses Stem Cells and the Future of Medicine

Posted by anna@stemsave.com on Apr 10, 2012 4:42:01 PM

 

 

 

 

 

Dr. Mao’s lecture focused on a variety of insights on the science, technology, and medical impact of stem cells and regenerative medicine including one of the overarching goals of stem cell researchers;reducing the health care expenditure in the US while delivering therapies and treatments that will lead to longer, healthier lives.

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Topics: Dr. Jeremy J. Mao, stemsaveblog, wisdom teeth, columbia university, bank dental stem cells, Dr. Jeremy Mao, dental stem cells, The Beckman Center, Phd, Distinctive Voices, DDS

Dr. Arnold Caplan Ph.D and Dr. Irina Kerkis Ph.D Publish Further Research on the Proliferative and Plastic Properties of Dental Pulp Stem Cells

Posted by anna@stemsave.com on Mar 23, 2012 12:50:23 PM

 

 

 

 

 

 

 

A research article recently published by Dr. Arnold Caplan Ph.D, and Dr. Irina Kerkis Ph.D examines the proliferative capabilities and plasticity of stem cells found in both baby teeth (DTSC) and adult wisdom teeth( DPSC).

By examining the origin and development of both types of teeth, the researchers found that both baby and wisdom teeth are highly proliferative and plastic, making them conducive to cryo-preservation and future harvesting. The article notes that stem cells derived from baby teeth have particular proliferative capacity because of the high concentration of stem cells in young teeth.

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Topics: Dr. Arnold Caplan, cryopreserve, stemsaveblog, wisdom teeth, cryopreservation, dental stem cells, Dr. Irina Kerkis, Arnold Caplan

AAOMS

AAOMS - American Association of Oral and Maxillofacial Surgeons

 

As the industry leader, StemSave is the only stem cell banking service to be designated as an ASI approved program.

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