Millions of individuals around the world suffer from type-1 diabetes, three million in the US alone. Researchers at the University of Missouri, led by Dr. Habib Zaghouani, have developed a two pronged approach to curing the disease: they modulate the immune system with a drug that stops it from attacking the pancreas and use stem cells to regenerate and rebuild the insulin producing pancreatic beta cells.
In a pre-clinical trial, Researchers at the National University of Ireland Galway have found that mesenchymal stem cells (MSCs) demonstrate the ability to increase wound healing for diabetics’ related wounds. Diabetic patients have impaired ability to heal wounds with 25% of diabetic patients affected by foot ulcers; which may result in amputation.
Like many forms of chronic disease, diabetes is on the rise in the U.S. and globally. Diabetes causes many complications, a very common symptom being the development of ulcers in feet. Often, this results in the amputation of the foot. In addition, according to Dr. Sankaranarayanan, "if left untreated, patients with diabetic foot ulcer may develop serious cardiac and renal complications."