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Stem Cell Treatment for Heart Damage Progresses to Phase 2 Clinical Trials

Posted by hunter@stemsave.com on Feb 23, 2014 9:27:56 AM

The progression of stem cell treatments is the only way to help the heart regenerate its own muscle.

Research teams from Cedars-Sinai Heart Institute and the Minneapolis Heart Institute with funding from CIRM [California Institute for Regenerative Medicine] are moving to Phase 2 Clinical Trials for a treatment that utilizes cardiac stem cells to repair severe heart damage. The treatment development was led by Eduardo Marbán, a director at the Cedars-Sinai Heart Institute and founder of Capricor. This groundbreaking treatment involves the injection of stem cells into the coronary artery, which then migrate to the heart and promote the regrowth of healthy heart muscle.

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Topics: Heart Valve, Phase III, Heart, stemsaveblog, Acute Myocardial Infarction, Heart Failure, clinical trials, Debilitating Diseases, Phase II, Stemcells, Heart Attack, autologousstemcells, heart disease

Heart Disease Treatment Utilizes Mesenchymal Stem Cells [MSCs]

Posted by pamela@stemsave.com on Jan 31, 2014 6:16:40 AM

Cell-Kro has the potential to rebuild damaged portions of the heart using the patient's own stem cells.

Researchers from the University of Vermont have developed a novel and effective application of mesenchymal stem cells [the same type found in Dental Stem Cells] to treat heart disease. The MSCs, when transplanted along with cardiac stem cells into the heart [in an animal model], produced a “cocktail” of protective ligands that improved the grafting success of the cardiac stem cells.

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Topics: Heart Valve, Heart, stemsaveblog, Heart Failure, clinical trials, Stemcells, Heart Attack, autologousstemcells, heart disease

Autologous Stem Cells Used to Reverse Heart Damage

Posted by taylor@stemsave.com on Jan 20, 2014 11:06:57 AM

By using the patient's own stem cells, Scientists have found a way to regenerate heart muscle tissue.

Utilizing autologous [the patient’s own]stem cells to regenerate heart muscle, scientists at the Novant Health Group have successfully treated patients that suffered from severe heart attacks; potentially limiting the long term loss of tissue and preserving heart function for victims. The patient’s own mesenchymal stem cells [the same type as dental stem cells] are harvested and then implanted back into the damaged area, where they recruit surrounding cells to aid in the repair process.

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Topics: Heart, stemsaveblog, Heart Failure, clinical trials, Stemcells, Heart Attack, autologousstemcells, heart disease

Mayo Clinic Advances Stem Cell Treatment for Heart Disease

Posted by maxi@stemsave.com on Nov 15, 2013 12:47:32 PM

Mayo Clinic Researchers have used autologous stem cells to treat heart disease

Mayo Clinic researchers from the Center of Regenerative Medicine have utilized a patient’s own stem cells in a novel treatment for heart disease. The treatment involves harvesting the patient’s own stem cells, expanding and differentiating them in-vitro [outside the body] and transplanting them back into the patient. As a result of the successful initial study, a wider clinical trial is planned.

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Topics: Heart, stemsaveblog, Heart Failure, clinical trials, Debilitating Diseases, Stemcells, Heart Attack, dentalstemcells, heart disease

Mayo Clinic - Replacing Pacemakers With Stem Cells

Posted by Kelsey StemSave on Sep 19, 2013 10:17:28 AM

Mayo Clinic researchers have resynchronized a disrupted heartbeat by using stem cells. Dr. Andre Terzic, a senior author of the study explained, “By harnessing the potential of regenerative medicine – repairing the injured heart, in this case – we will be increasingly able to provide more definitive solutions to our patients”.

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Topics: Heart, stemsaveblog, Heart Failure, Stemcells, Heart Attack, heart disease

Stem Cells Utilized to Create BioBots

Posted by hunter@stemsave.com on Sep 4, 2013 5:10:35 PM

BioBot

An interdisciplinary approach at the University of Illinois enabled researchers to combine 3D printing and stem cells to create “biobots”. A “biobot” is defined as a biological machine; in this case it was made with hydrogel, heart stem cells, and a 3D printer. In a scene reminiscent of the 1966 sci-fi movie ‘The Fantastic Voyage’ the research points to the development of small [tiny] ‘biobots’ that could travel within the body identifying cancers or toxins and enabling precision delivery of drugs or other treatments.

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Topics: Heart, stemsaveblog, Heart Failure, Stemcells, Heart Attack, heart disease

Avoiding Heart Transplants with the Use of Stem Cells

Posted by Kelsey StemSave on Aug 21, 2013 7:14:53 AM

Dr. Ganesh Raveendran, MD, MS

Dr. Ganesh Raveendran, MD, MS, Director, Cardiac Catheterization Laboratory at the University of Minnesota Medical Center is conducting a clinical study using autologous [the patient’s own] stem cells to treat patients requiring Left-Ventricular Assist Devices (LVADs). The clinical study hopes to create a viable alternative for patients that might otherwise require a complete heart transplant. According to Dr. Raveendran, “there are only 2,500 heart transplants done annually in this country [USA], whereas more than 100,000 patients are waiting to get heart transplants. So there is a gap between patients who need hearts and the number of patients who can get hearts.” The success of the treatment would eliminate the need for many heart transplants and provide a viable alternative to individuals awaiting a heart transplant [where there is a shortage of hearts].

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Topics: Heart, stemsaveblog, Heart Failure, clinical trials, Stemcells, Heart Attack, autologousstemcells, heart disease

Cardiac Patches From Stem Cells Advances Heart Failure Treatment

Posted by taylor@stemsave.com on Jul 10, 2013 10:26:33 AM

biowire

Researchers at the University of Toronto, led by Milica Radisic, Canada Research Chair in Functional Cardiovascular Tissue Engineering and Associate Professor at the Institute of Biomaterials & Biomedical Engineering (IBBME) and the Department of Chemical Engineering, have developed a multidisciplinary technique for maturing human heart cells. The new technique, referred to as “biowire,” enables scientists to differentiate stem cells into beating cardiomyocites in vitro [outside the body]. Researchers envision utilizing the technique to create cardiac patches for transplantation to replace damaged tissue for those suffering from heart failure. Heart disease is the leading cause of death in the United States.

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Topics: Heart, stemsaveblog, Heart Failure, Stemcells, Heart Attack, heart disease

Mayo Clinic Utilizes Autologous Stem Cells to Treat Heart Failure Patients in First Clinical Study to Target the Regeneration of a Failing Organ

Posted by taylor@stemsave.com on Jun 7, 2013 2:58:53 PM

Researchers at Mayo Clinic have introduced a new therapy using cardiogenically-instructed stem cells that can improve heart health. This is the first clinical study for the targeted regeneration of a failing organ. The Mayo Clinic study represents what we believe to be the gold standard in regenerative treatments – utilizing the patient’s own stem cells for the therapy. As a result of the use of autologous [the patient’s own] stem cells, there were no complications in any of the patients. Every patient in the stem cell treatment group improved. "The benefit to patients who received cardiopoietic stem cell therapy was significant," said Dr. Terzic – the senior author of the study, with improvements in heart pumping function, physical performance (such as walking distance) and overall quality of life.

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Topics: Heart, stemsaveblog, Heart Failure, clinical trials, Stemcells, Heart Attack, autologousstemcells, Ischemic Cardiomyopathy, heart disease

Mayo Clinic Utilizes Autologous Stem Cells to Treat Heart Failure Patients in First Clinical Study to Target the Regeneration of a Failing Organ

Posted by taylor@stemsave.com on Jun 7, 2013 2:58:53 PM

Researchers at Mayo Clinic have introduced a new therapy using cardiogenically-instructed stem cells that can improve heart health. This is the first clinical study for the targeted regeneration of a failing organ. The Mayo Clinic study represents what we believe to be the gold standard in regenerative treatments – utilizing the patient’s own stem cells for the therapy. As a result of the use of autologous [the patient’s own] stem cells, there were no complications in any of the patients. Every patient in the stem cell treatment group improved. "The benefit to patients who received cardiopoietic stem cell therapy was significant," said Dr. Terzic – the senior author of the study, with improvements in heart pumping function, physical performance (such as walking distance) and overall quality of life.

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Topics: Dr. Terzic, Heart, stemsaveblog, Heart Failure, clinical trials, Stemcells, clinical trial, Heart Attack, Mayo Clinic, autologousstemcells, Ischemic Cardiomyopathy, heart disease

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AAOMS - American Association of Oral and Maxillofacial Surgeons

 

As the industry leader, StemSave is the only stem cell banking service to be designated as an ASI approved program.

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