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Low Blood Cell Counts Could Be Treated by Regulating Stem Cells.

Posted by barb@stemsave.com on Dec 16, 2014 11:22:59 AM

Megakaryotes may hold the ability to regulate the amount of blood that stem cells produce.

According to new research from the Stowers Institute for Medical Research, hematopoietic stem cells [stem cells that produce blood] are directly regulated by megakaryocytes, the blood cells responsible for healing wounds. The researchers found that megakaryotes produce two growth factors; one that signals for hematopoietic stem cells to proliferate, and one that keeps them in an inactive state. This relationship controls the amount of blood being produced in the body.

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Topics: Artery, Blood Cancer, stemsaveblog, Metachromatic Leukodystrophy, Debilitating Diseases, Stemcells, autologousstemcells, hematological malignancies, Blood vessel

Blood Cells Generated by Modified Stem Cell Differentiation

Posted by taylor@stemsave.com on Oct 13, 2014 12:20:57 PM

Researchers have identified two transcription factors that induce stem cells to differentiate into blood cells.

A research group led by Dr. Igor Slukvin, MD PHD, from University of Wisconsin-Madison has identified two transcription factors responsible for the differentiation of stem cells into numerous types of white and red blood cells. The team made use of messenger RNA to overexpress the two transcription factors, which allowed them to generate 30 million blood cells for every million stem cells, without the use of a virus or altering the genetic structure of the blood.

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Topics: Artery, stemsaveblog, RNA probe, Debilitating Diseases, Stemcells, autologousstemcells, hematological malignancies, Blood vessel, young stem cells

Improving the Efficacy of Hematopoietic Stem Cells.

Posted by pamela@stemsave.com on Aug 11, 2014 6:58:53 AM

The protein SIRT1 maintains the regenerative abilities of hematopoietic stem cells.

A research team from Mount Sinai, Harvard Medical School, and Children’s Hospital in Boston has determined the function of protein Sirtuin1 (SIRT1) in maintaining the regenerative ability of blood stem cells. The researchers found that young stem cells lacking SIRT1 exhibited a similar deficiency in rejuvenating blood as observed in older stem cells. These older, defunct blood stem cells are unable to refresh the body’s blood supply, resulting in vulnerability to age-related cancers and immune diseases.

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Topics: stemsaveblog, Debilitating Diseases, Stemcells, autologousstemcells, hematological malignancies, Blood vessel

Stem Cell Treatments for Hematological Malignancies Advance to Clinical Testing Phase

Posted by devin@stemsave.com on Oct 15, 2012 6:30:14 AM

Gamida Cell, a leading adult stem cell therapeutics company has completed enrollment for a Phase I/II trial for hematological malignancies utilizing their NiCord treatment. The treatment is a potential cure for blood cancers, sickle cell disease, thalassemia, severe autoimmune diseases and metabolic diseases. This trial is but one example of the increasing number of stem cell treatments moving out of the lab and entering the clinical testing phase.

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Topics: sickle cell disease, Phase III, Blood Cancer, stemsaveblog, clinical trials, Stemcells, hematological malignancies

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AAOMS

AAOMS - American Association of Oral and Maxillofacial Surgeons

 

As the industry leader, StemSave is the only stem cell banking service to be designated as an ASI approved program.

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