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Stem Cell Matrix Advances Potential Treatments for Metabolic Disorders

Posted by on Nov 18, 2016 12:31:10 PM

When stem cells are taken out of the body and placed in cultures, the microenvironment that permits the generation of an extracellular matrix is lost, impacting their functionality. To address this shortcoming, a team of researchers from A*STAR Institute of Medical Biology - led by Michael Raghunath and Cedric Badowski, in conjunction with scientists at the National University of Singapore utilized a technique termed 'macromolecular crowding’ [that mimics the microenvironment of the cells] to encourage stem cell differentiation and regeneration.

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Topics: metabolic diseases, regenerative therapies, brown fat, mesenchymal stem cells, macromolecular crowding


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