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Dental Stem Cells Used in Parkinson’s Treatment

Posted by davids@stemsave.com on Feb 4, 2019 11:08:00 AM

Researchers are utilizing vesicles secreted from dental stem cells to treat Parkinson’s Disease (PD). The study utilized these vesicles secreted by stem cells, as they are small and can easily cross the blood-brain barrier to deliver a treatment to the parts of the brain affected by PD. Parkinson’s is a neuro-degenerative disorder that affects the part of the brain that produces a neurotransmitter called dopamine, with symptoms expressing themselves as tremors and limb rigidity, among others. This study demonstrated, in an animal model, that intranasal administration of dental stem cell vesicles had a therapeutic effect by regulating the expression of proteins and preventing dopaminergic neuron death. The results showed a decrease in PD tremors and showed no adverse neurological effects over the progression of the study.

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Topics: parkinsons disease, dental stem cells, mesenchymal stem cells, regenerative medicine, autologous stem cells, stem cell treatment

Alzheimer’s Treated With Stem Cells

Posted by anna@stemsave.com on Jan 21, 2019 10:19:00 AM

In a Phase II clinical trial, researchers are using autologous (the patients’ own) mesenchymal stem cells to treat Alzheimer’s disease. According to the Centers for Disease Control (CDC) 5.7 million Americans are currently suffering from Alzheimer’s [with approximately 5.5 million over the age of 65 and approximately 220k under 65 experiencing early onset Alzheimer’s] with the number expected to triple by 2060. Additionally, the disease is one of the top 10 leading causes of death in U.S. adults; and while incidents of other common ailments like heart disease and cancer are decreasing, Alzheimer’s is on the rise.

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Topics: Alzheimer's disease, Phase I/II clinical trial, treating Alzheimer's, mesenchymal stem cells, autologous stem cells, stem cell treatment

Repairing Permanent Corneal Damage with Stem Cells

Posted by pamela@stemsave.com on Jan 8, 2019 1:20:00 PM

Researchers at Stanford University and the University of Illinois at Chicago are utilizing factors secreted from stem cells to repair severe corneal damage and scarring, which causes severe side effects, including blindness. This study utilizes a novel approach that delivers the treatment directly to the site of the injury compared to conventional treatments. Typically, corneal damage is treated with lubricating drops, steroids and patching the injury site, but this novel treatment approach seeks to treat the symptoms of the injury and repair the scar tissue completely. The treatment involves using repair factors secreted by mesenchymal stem cells, along with a biological gel made of hyaluronic acid and chondroitin sulfate which promote the regeneration of the cornea membrane.

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Topics: corneal disease, Blindness, mesenchymal stem cells, corneal damage, corneal injury

Lifesaving Platelets Created with Stem Cells

Posted by maxi@stemsave.com on Jan 3, 2019 3:32:00 PM

Researchers at Keio University in Tokyo have developed a method to generate platelets negating the need to obtain them from donated blood. Typically, platelets come from blood donations and have an extremely short shelf-life of 5 days. Platelets are vital to a great number and variety of medical procedures as they are responsible for clotting and can prevent patients from bleeding out from serious injuries or during surgeries. Additionally, platelets are difficult to match from donor to patient and donated platelets run the risk of rejection by the recipient. Creating a patient’s own platelets from their own stem cells would negate the need for a donor and virtually eliminate any possibility of rejection. Generating patient specific platelets would also alleviate the shortages that are typical of the current platelet recovery environment.

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Topics: blood cells, mesenchymal stem cells, platelets, stem cell use

Soccer Star Luis Suarez Scores with Stem Cells

Posted by davids@stemsave.com on Nov 14, 2018 2:29:00 PM

Luis Suarez, a star of FC Barcelona, will undergo a stem cell treatment to alleviate pain in his knee and prevent further injury. Suarez has been dealing with intermittent spurs of pain, and a traumatic crash during a recent match exacerbated his injury and may have sidelined him for several weeks. However, Suarez’s stem cell treatment should have him back on the field in approximately 2-week's-time.

The treatment involves recovering the patient’s own stem cells (in this case mesenchymal stem cells - the same type of stem cells found in teeth), concentrating them and injecting them into the site of the injury to accelerate healing, decrease inflammation and eliminate the need for surgical intervention.

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Topics: mesenchymal stem cells, autologous stem cells, chronic pain, professional athlete, stem cell injection, knee injury treatment, sports injuries

Stem Cells Accelerate Diabetic Wound Healing

Posted by davids@stemsave.com on Oct 22, 2018 3:04:00 PM

Mesenchymal stem cells (MSCs) have been found to be effective in accelerating healing time for diabetics. In patients with diabetes, high blood sugar levels negatively impact circulation and impair the immune system’s ability to fight off infections at the site of wounds. In an animal study, adipose derived MSCs, proved to be effective at decreasing inflammation and increasing circulation around wounds. Previous studies have utilized MSCs recovered from bone marrow. This study demonstrates the potential of MSCs, which can be derived from multiple sources, including teeth, to treat the millions of diabetics around the world who suffer from this debilitating affliction.

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Topics: Type-1 Diabetes, diabetic wounds, type 2 diabetes, treating diabetes, mesenchymal stem cells, stem cell diabetes treatment

Rheumatoid Arthritis Stem Cells Treatment

Posted by pamela@stemsave.com on Oct 16, 2018 1:43:00 PM

A case study utilizing a patient’s own stem cells to treat rheumatoid arthritis demonstrated a drastic decrease in joint pain and inflammation. Rheumatoid Arthritis (RA) occurs when the immune system incorrectly attacks the body’s tissues, eventually leading to joint deformities, bone erosion and intense pain due to the breakdown of the lining of the joint. Typical treatments for RA involve anti-inflammatory medications, or surgery to repair the joints. However, both types of treatments involve severe side effects and are not guaranteed to work. The stem cell treatment sighted in the case study holds the potential to radically upend current practices and create a new standard of care for this widespread disorder.

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Topics: Rheumatoid Arthritis, autoimmune disease, stem cell therapy, mesenchymal stem cells, autologous stem cells, arthritis treatment

Stem Cells Help Patients Following Chemo/Radiation

Posted by barb@stemsave.com on Sep 28, 2018 11:41:00 AM

Researchers are utilizing mesenchymal stem cell (MSC) infusions to help heal severe tissue damage following radiation treatments. Often, when patients receive treatment for cancer, the process involves painful and prolonged side effects from the chemotherapy and radiation, which significantly impacts the patients’ quality of life, even when in remission. MSC intravenous infusions demonstrated both healing properties and resulted in a reduction of pain and fistulization (the abnormal connections between organs due to injury and inflammation) following radiation. The patients receiving the treatment had sustained intestinal tissue damage following radiation treatments, and prior to the treatment all patients were experiencing pain, inflammation, fibrosis and hemorrhaging.

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Topics: stem cell therapy, mesenchymal stem cells, cancer treatment, radiation treatments

DoD Sponsors Eye Injury Stem Cell Treatment

Posted by taylor@stemsave.com on Sep 15, 2018 1:09:00 PM

The University of Illinois at Chicago has received a $5.25 million grant from the Department of Defense [DoD] to develop clinical trials using stem cells to treat eye injuries and expedite healing. The treatments utilize mesenchymal stem cells (the same type of stem cells found in teeth) due to their anti-inflammatory and immunomodulatory properties, which can help heal scarring and preserve eyesight. The treatments are targeted for combat veterans injured due to explosions and chemical burns to the eye, but could also be used to treat chronic corneal injuries in other patients.

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Topics: corneal burns,, mesenchymal stem cells, eye injuries

Lupus Stem Cell Study Endorsed by National Institutes of Health (NIH)

Posted by maxi@stemsave.com on Jun 20, 2018 5:49:00 PM

A phase II clinical study investigating the efficacy of mesenchymal stem cells [MSCs] to treat moderate to severe lupus symptoms has been launched by the Lupus Foundation of America, in collaboration with the National Institute of Allergy and Infectious Diseases (part of the NIH). Lupus is a chronic autoimmune disorder in which the immune system can affect virtually any tissue in the body, including skin, joints and organs. MSCs represent a promising treatment option in that, in addition to the inherent plasticity of MSCs, they also possess immune modulation properties.  The NIH is providing resources and oversight for the study, which will investigate how mesenchymal stem cells can effectively regulate and limit the autoimmune response of Lupus sufferers.  Currently there are no effective options for their lupus symptoms other than steroid treatments, which have significant side effects, as they are detrimental to vital organ function.

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Topics: stem cell therapy, lupus, mesenchymal stem cells, regenerative treatments

AAOMS

AAOMS - American Association of Oral and Maxillofacial Surgeons

 

As the industry leader, StemSave is the only stem cell banking service to be designated as an ASI approved program.

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