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Deciphering Stem Cells’ Messages

Posted by on Apr 25, 2016 3:37:00 PM

Although we understand stem cell’s role in the body, the subtleties of extracellular communication remain a difficult system to analyze. An international group of researchers has recently discovered an intricate cell-to-cell communications system used by stem cells. The findings will help scientists develop new stem cell-based treatment options for peripheral artery disease, a condition which affects about 12 million people in the United States alone.

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Topics: stemsaveblog, Peripheral Arterial Disease, stem cells, cell communication

Atherosclerotic Lesions Prevented by MSCs

Posted by on Feb 10, 2015 5:23:51 AM

Stem cells were found to reduce plaque in patients with atherosclerosis.

According to new research from the National Yang-Ming University, mesenchymal stem cells [MSCs] hold the ability to limit atherosclerotic plaque formation, thereby preventing the onset of harmful endothelial lesions. The research team, led by Shih-Chieh Hung, transplanted MSCs into animal models with atherosclerosis and observed significant reduction in plaque formation. They also saw an increase in blood vessel dilation, which prevents further plaque development, indicating good endothelial health.

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Topics: Artery, limbs, Heart, stemsaveblog, Heart Failure, Debilitating Diseases, Stemcells, autologousstemcells, Blood vessel, Peripheral Arterial Disease

Peripheral Artery Disease Treatment Utilizes Stem Cells

Posted by on Nov 12, 2014 9:34:00 AM

Scientists have devised a method of regenerating blood vessels by transplanting stem cells.

Researchers from the Indiana University School of Medicine have developed a potential therapy for peripheral artery disease by transplanting autologous [the patient’s own] stem cells. In an animal model, the transplanted stem cells differentiated into new blood vessels, which then restored blood flow to damaged tissues in the body.

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Topics: Artery, stemsaveblog, Debilitating Diseases, Stemcells, autologousstemcells, Blood vessel, Peripheral Arterial Disease

Autologous Stem Cell Treatment for Peripheral Arterial Disease [PAD]

Posted by on Jul 5, 2013 10:46:41 AM

Peripheral Arterial Disease

University Hospital’s Case Medical Center researchers are to begin evaluating the ability of the patient’s own stem cells [autologous stem cells] to prevent leg amputations in peripheral arterial disease. PAD effects more than 5 million adults in the US alone. Dr. Vik Kashyap, the leading researcher, explained, "This trial offers an opportunity to save a patient's leg when there are no remaining options to improve blood supply.”

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Topics: stemsaveblog, clinical trials, Stemcells, autologousstemcells, Peripheral Arterial Disease


AAOMS - American Association of Oral and Maxillofacial Surgeons


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