A group of international scientists led by Dr. Macchiarini, professor of regenerative medicine at Karolinska Institute, has successfully engineered diaphragm tissue in animal models using a mixture of stem cells and 3D scaffolds. When the cells are transplanted, they demonstrate the same complex mechanical properties as diaphragm muscle. This offers hope for common birth defects and possible future heart muscle repairs.
Recently published research out of South Korea has presented a new method of differentiating mesenchymal stem cells [MSCs] into liver cells for autologous use in regenerative medicine. Geneticists found that the overexpression of two genes within MSCs, oct4 and sox2, resulted in the stem cells converting into fully functional hepatocytes, or liver cells, capable of producing urea and storing glycogen.
Topics: hepatocytes, liver cells, regenerate organs, Stemcells, stem cell differentiation, Liver disease, research, StemSave, mesenchymal stem cells, autologous stem cells, stem cells, biology, adult stem cells