In a recently published study from the Hallym University College of Medicine, researchers have applied mesenchymal stem cells [MSCs] to animal models afflicted with global cerebral ischemia [GCI] to successfully reduce the associated neuronal damage. When compared to those that received no treatment, animals that received MSCs displayed a significant decrease in cell death, inflammation to the brain, and disruption of the blood brain barrier.
Autologous stem cell therapy has shown significant signs of recovery in acute stroke patients.
In a pilot study conducted by the Imperial College Healthcare NHS Trust, five patients received transplants of their own [autologous] stem cells directly into their brains only seven days after a severe stroke. Although the trial was designed primarily to assess the safety of such a procedure, the patients showed significant signs of recovery considering the typical lethality of the strokes.
Peter Couche suffered from a stroke 20 years ago and has since lived with ‘Locked-in Syndrome’. Peter established The Peter Couche Foundation within the Robinson Institute at the University of Adelaide. The foundation raises money to support adult stem cells research on treatments for stroke victims. The University research utilizes the powerful stem cells found in teeth to develop regenerative therapies to address the trauma induced as a result of a stroke. As the research advances, scientists envisage a therapy regiment utilizing autologous [from the patient] dental stem cells.
Stroke is the third largest cause of death and the single largest cause of adult disability in the developed world. The University of Glasgow and ReNeuron are advancing their clinical trial for stroke patients using neuronal stem cells. Approved by the UK Medicines and Healthcare Products Regulatory Agency (MHRA), the procedure involves expanding the stem cells in-vitro [to clinically relevant numbers] and then transplanting them into the individual. Professor Keith Muir, principal investigator in the trial, said: “We are very pleased that the trial is progressing well and that all the patients treated so far have shown no adverse effects.”
A symposium, to be held on May 4th in Austin Texas and entitled "Collaborating for Cures: Emerging Translational Research in the Stroke and TBI Care Continuum" is advocating and embracing a multidisciplinary approach to treating traumatic brain injuries and providing cutting-edge medical care.
Topics: Texans for Stem Cell Research, stroke, Tom Caven, CORE Health Foundation, bank dental stem cells, stroke recovery, brain injury, Stanley Wang, Texas Cures Education Foundation, traumatic brain injury treatment, stemsaveblog