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Under Pressure – Stem Cell Differentiation Triggered by Mechanical Force.

Posted by pamela@stemsave.com on Apr 2, 2015 11:12:16 AM

Scientists have found that mechanical pressure determines the fate of certain stem cells.

Bioengineers from the University of California, San Diego, have identified a mechanism by which stem cell differentiation is regulated by the exertion of mechanical pressure.  Using optical tweezers to apply mechanical force to stem cells, the researchers, led by Dr. Yingxiao Wang, observed the release of calcium ions, which are critical in the cellular communication required for stem cell differentiation.  Dr. Wang’s team concluded that the forces of a stem cell’s environment, such as the tension inside the jaw, can promote the cell’s maturation into stiff tissue like bone or cartilage.

The ability to influence a stem cell’s path to differentiation is a crucial asset in the field of regenerative medicine.  This new insight into a key signaling pathway can guide scientists in recreating these mechanisms for the development of new transplants and therapies for the improvement of patient outcomes.

The University of California, San Diego’s research is an example of how scientists are gaining insights that will facilitate more effective treatments leading to better outcomes.  To learn more about the value of preserving your own stem cells for use in future therapies and how to bank your own stem cells through a non-evasive and affordable method by recovering your dental pulp stem cells, visit StemSave or call 877-783-6728 (877-StemSave) today.

 

 

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The Future of Regenerative Medicine is Now™.

Topics: Bone loss, stemsaveblog, Bone, repair cartilage, bone regeneration, stem cell differentiation, University of California San Diego, mechanical pressure,, pressure, calcium,

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AAOMS - American Association of Oral and Maxillofacial Surgeons

 

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